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Oral administration of TRAIL-inducing small molecule ONC201/TIC10 prevents intestinal polyposis in the Apc min/+ mouse model.
Madka V, De La Cruz A, Pathuri G, Panneerselvam J, Zhang Y, Stratton N, Hacking S, Finnberg NK, Safran HP, Sei S, Glaze ER, Shoemaker R, Fox JT, Raufi AG, El-Deiry WS, Rao CV. Madka V, et al. Among authors: glaze er. Am J Cancer Res. 2022 May 15;12(5):2118-2131. eCollection 2022. Am J Cancer Res. 2022. PMID: 35693092 Free PMC article.
Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist.
Horn TL, Harder JB, Johnson WD, Curry PT, Parchment RE, Morrissey RL, Mellick PW, Calis KA, Gold PW, Rice KC, Contoreggi C, Charney DS, Cizza G, Glaze ER, Tomaszewski JE, McCormick DL. Horn TL, et al. Among authors: glaze er. Toxicology. 2008 Jun 3;248(1):8-17. doi: 10.1016/j.tox.2008.03.002. Epub 2008 Mar 13. Toxicology. 2008. PMID: 18423834 Free PMC article.
Preclinical toxicity of a geldanamycin analog, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG), in rats and dogs: potential clinical relevance.
Glaze ER, Lambert AL, Smith AC, Page JG, Johnson WD, McCormick DL, Brown AP, Levine BS, Covey JM, Egorin MJ, Eiseman JL, Holleran JL, Sausville EA, Tomaszewski JE. Glaze ER, et al. Cancer Chemother Pharmacol. 2005 Dec;56(6):637-47. doi: 10.1007/s00280-005-1000-9. Epub 2005 Jun 29. Cancer Chemother Pharmacol. 2005. PMID: 15986212