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Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.
Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DDS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; UK Cystic Fibrosis Gene Therapy Consortium. Alton EWFW, et al. Among authors: smith k, smith sn. Lancet Respir Med. 2015 Sep;3(9):684-691. doi: 10.1016/S2213-2600(15)00245-3. Epub 2015 Jul 3. Lancet Respir Med. 2015. PMID: 26149841 Free PMC article. Clinical Trial.
A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis.
Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; on behalf of the UK Cystic Fibrosis Gene Therapy Consortium. Alton EWFW, et al. Among authors: smith k, smith sn. Southampton (UK): NIHR Journals Library; 2016 Jul. Southampton (UK): NIHR Journals Library; 2016 Jul. PMID: 27441329 Free Books & Documents. Review.
Transcriptome-wide outlier approach identifies individuals with minor spliceopathies.
Arriaga MT, Mendez R, Ungar RA, Bonner DE, Matalon DR, Lemire G, Goddard PC, Padhi EM, Miller AM, Nguyen JV, Ma J, Smith KS, Scott SA, Liao L, Ng Z, Marwaha S, Bademci G, Bivona SA, Tekin M; Undiagnosed Disease Network; Genomics Research to Elucidate the Genetics of Rare Diseases consortium; Bernstein JA, Montgomery SB, O'Donnell-Luria A, Wheeler MT, Ganesh VS. Arriaga MT, et al. Among authors: smith ks. medRxiv [Preprint]. 2025 Jan 3:2025.01.02.24318941. doi: 10.1101/2025.01.02.24318941. medRxiv. 2025. PMID: 39802771 Free PMC article. Preprint.
Art of leading quality improvement.
Coffey M, Smith K. Coffey M, et al. Among authors: smith k. BMJ Qual Saf. 2025 Jan 11:bmjqs-2024-017909. doi: 10.1136/bmjqs-2024-017909. Online ahead of print. BMJ Qual Saf. 2025. PMID: 39798991 No abstract available.
Human Health Surveillance During Animal Disease Emergencies: Minnesota Department of Health Response to Highly Pathogenic Avian Influenza Outbreaks, 2015 and 2022-2023.
Scheftel JM, Schenk KE, Bauck LJ, Bye ML, Ireland MJ, Klumb CA, Kollmann LM, Smith KE, Voss SJ, Hoefs BL, Hunt LJ, Holzbauer SM. Scheftel JM, et al. Among authors: smith ke. J Agromedicine. 2025 Jan 9:1-12. doi: 10.1080/1059924X.2024.2442406. Online ahead of print. J Agromedicine. 2025. PMID: 39783998
One-quarter of freshwater fauna threatened with extinction.
Sayer CA, Fernando E, Jimenez RR, Macfarlane NBW, Rapacciuolo G, Böhm M, Brooks TM, Contreras-MacBeath T, Cox NA, Harrison I, Hoffmann M, Jenkins R, Smith KG, Vié JC, Abbott JC, Allen DJ, Allen GR, Barrios V, Boudot JP, Carrizo SF, Charvet P, Clausnitzer V, Congiu L, Crandall KA, Cumberlidge N, Cuttelod A, Dalton J, Daniels AG, De Grave S, De Knijf G, Dijkstra KB, Dow RA, Freyhof J, García N, Gessner J, Getahun A, Gibson C, Gollock MJ, Grant MI, Groom AER, Hammer MP, Hammerson GA, Hilton-Taylor C, Hodgkinson L, Holland RA, Jabado RW, Juffe Bignoli D, Kalkman VJ, Karimov BK, Kipping J, Kottelat M, Lalèyè PA, Larson HK, Lintermans M, Lozano F, Ludwig A, Lyons TJ, Máiz-Tomé L, Molur S, Ng HH, Numa C, Palmer-Newton AF, Pike C, Pippard HE, Polaz CNM, Pollock CM, Raghavan R, Rand PS, Ravelomanana T, Reis RE, Rigby CL, Scott JA, Skelton PH, Sloat MR, Snoeks J, Stiassny MLJ, Tan HH, Taniguchi Y, Thorstad EB, Tognelli MF, Torres AG, Torres Y, Tweddle D, Watanabe K, Westrip JRS, Wright EGE, Zhang E, Darwall WRT. Sayer CA, et al. Among authors: smith kg. Nature. 2025 Jan 8. doi: 10.1038/s41586-024-08375-z. Online ahead of print. Nature. 2025. PMID: 39779863
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