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Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.
Ye N, Zhu Y, Chen H, Liu Z, Mei FC, Wild C, Chen H, Cheng X, Zhou J. Ye N, et al. Among authors: chen h. J Med Chem. 2015 Aug 13;58(15):6033-47. doi: 10.1021/acs.jmedchem.5b00635. Epub 2015 Jul 16. J Med Chem. 2015. PMID: 26151319 Free PMC article.
Targeting Krüppel-like factor 5 (KLF5) for cancer therapy.
Gao Y, Ding Y, Chen H, Chen H, Zhou J. Gao Y, et al. Among authors: chen h. Curr Top Med Chem. 2015;15(8):699-713. doi: 10.2174/1568026615666150302105052. Curr Top Med Chem. 2015. PMID: 25732792 Review.
Direct Activation of Bax Protein for Cancer Therapy.
Liu Z, Ding Y, Ye N, Wild C, Chen H, Zhou J. Liu Z, et al. Among authors: chen h. Med Res Rev. 2016 Mar;36(2):313-41. doi: 10.1002/med.21379. Epub 2015 Sep 23. Med Res Rev. 2016. PMID: 26395559 Free PMC article. Review.
BH4 domain of Bcl-2 as a novel target for cancer therapy.
Liu Z, Wild C, Ding Y, Ye N, Chen H, Wold EA, Zhou J. Liu Z, et al. Among authors: chen h. Drug Discov Today. 2016 Jun;21(6):989-96. doi: 10.1016/j.drudis.2015.11.008. Epub 2015 Nov 26. Drug Discov Today. 2016. PMID: 26631752 Free PMC article. Review.
Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors.
Wild CT, Zhu Y, Na Y, Mei F, Ynalvez MA, Chen H, Cheng X, Zhou J. Wild CT, et al. Among authors: chen h. ACS Med Chem Lett. 2016 Mar 28;7(5):460-4. doi: 10.1021/acsmedchemlett.5b00477. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190593 Free PMC article.
Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach.
Chao C, Zatarain JR, Ding Y, Coletta C, Mrazek AA, Druzhyna N, Johnson P, Chen H, Hellmich JL, Asimakopoulou A, Yanagi K, Olah G, Szoleczky P, Törö G, Bohanon FJ, Cheema M, Lewis R, Eckelbarger D, Ahmad A, Módis K, Untereiner A, Szczesny B, Papapetropoulos A, Zhou J, Hellmich MR, Szabo C. Chao C, et al. Among authors: chen h. Mol Med. 2016 Sep;22:361-379. doi: 10.2119/molmed.2016.00102. Epub 2016 May 16. Mol Med. 2016. PMID: 27257787 Free PMC article.
95,108 results
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