Joel P - Search Results

1

Vascular disease-causing mutation R258C in ACTA2 disrupts actin dynamics and interaction with myosin.

Lu H, Fagnant PM, Bookwalter CS, Joel P, Trybus KM. Lu H, et al. Among authors: joel p. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4168-77. doi: 10.1073/pnas.1507587112. Epub 2015 Jul 7. Proc Natl Acad Sci U S A. 2015. PMID: 26153420 Free PMC article.

2

Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels.

Lowey S, Bretton V, Joel PB, Trybus KM, Gulick J, Robbins J, Kalganov A, Cornachione AS, Rassier DE. Lowey S, et al. Among authors: joel pb. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11238-11243. doi: 10.1073/pnas.1802967115. Epub 2018 Oct 15. Proc Natl Acad Sci U S A. 2018. PMID: 30322937 Free PMC article.

3

Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly.

Sitar T, Gallinger J, Ducka AM, Ikonen TP, Wohlhoefler M, Schmoller KM, Bausch AR, Joel P, Trybus KM, Noegel AA, Schleicher M, Huber R, Holak TA. Sitar T, et al. Among authors: joel p. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19575-80. doi: 10.1073/pnas.1115465108. Epub 2011 Nov 21. Proc Natl Acad Sci U S A. 2011. PMID: 22106272 Free PMC article.

4

Addition of lysines to the 50/20 kDa junction of myosin strengthens weak binding to actin without affecting the maximum ATPase activity.

Joel PB, Sweeney HL, Trybus KM. Joel PB, et al. Biochemistry. 2003 Aug 5;42(30):9160-6. doi: 10.1021/bi034415j. Biochemistry. 2003. PMID: 12885250

5

A mutant heterodimeric myosin with one inactive head generates maximal displacement.

Kad NM, Rovner AS, Fagnant PM, Joel PB, Kennedy GG, Patlak JB, Warshaw DM, Trybus KM. Kad NM, et al. J Cell Biol. 2003 Aug 4;162(3):481-8. doi: 10.1083/jcb.200304023. J Cell Biol. 2003. PMID: 12900396 Free PMC article.

6

Expression of a nonpolymerizable actin mutant in Sf9 cells.

Joel PB, Fagnant PM, Trybus KM. Joel PB, et al. Biochemistry. 2004 Sep 14;43(36):11554-9. doi: 10.1021/bi048899a. Biochemistry. 2004. PMID: 15350141

7

Crystal structures of monomeric actin bound to cytochalasin D.

Nair UB, Joel PB, Wan Q, Lowey S, Rould MA, Trybus KM. Nair UB, et al. J Mol Biol. 2008 Dec 26;384(4):848-64. doi: 10.1016/j.jmb.2008.09.082. Epub 2008 Oct 10. J Mol Biol. 2008. PMID: 18938176 Free PMC article.

8

Two conserved lysines at the 50/20-kDa junction of myosin are necessary for triggering actin activation.

Joel PB, Trybus KM, Sweeney HL. Joel PB, et al. J Biol Chem. 2001 Feb 2;276(5):2998-3003. doi: 10.1074/jbc.M006930200. Epub 2000 Oct 20. J Biol Chem. 2001. PMID: 11042210 Free article.

9

Crystal structures of expressed non-polymerizable monomeric actin in the ADP and ATP states.

Rould MA, Wan Q, Joel PB, Lowey S, Trybus KM. Rould MA, et al. J Biol Chem. 2006 Oct 20;281(42):31909-19. doi: 10.1074/jbc.M601973200. Epub 2006 Aug 18. J Biol Chem. 2006. PMID: 16920713 Free article.

10

Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.

Ducka AM, Joel P, Popowicz GM, Trybus KM, Schleicher M, Noegel AA, Huber R, Holak TA, Sitar T. Ducka AM, et al. Among authors: joel p. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11757-62. doi: 10.1073/pnas.1005347107. Epub 2010 Jun 10. Proc Natl Acad Sci U S A. 2010. PMID: 20538977 Free PMC article.

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