Use of spoligotyping to study the evolution of the direct repeat locus by IS6110 transposition in Mycobacterium tuberculosis.
Legrand E, Filliol I, Sola C, Rastogi N.
Legrand E, et al. Among authors: sola c.
J Clin Microbiol. 2001 Apr;39(4):1595-9. doi: 10.1128/JCM.39.4.1595-1599.2001.
J Clin Microbiol. 2001.
PMID: 11283094
Free PMC article.
It was recently hypothesized that despite its presence in the DR locus, spacer 31 could not be amplified in M. tuberculosis clinical isolates belonging to spoligotype 50 due to the insertion of an extra copy of IS6110 between spacers 31 and 32 that could lead to an asymmetrical s …
It was recently hypothesized that despite its presence in the DR locus, spacer 31 could not be amplified in M. tuberculosis clinical isolate …