Krintel C - Search Results

1

Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity.

Shahsavar A, Ahring PK, Olsen JA, Krintel C, Kastrup JS, Balle T, Gajhede M. Shahsavar A, et al. Among authors: krintel c. Mol Pharmacol. 2015 Oct;88(4):697-707. doi: 10.1124/mol.115.098061. Epub 2015 Jul 15. Mol Pharmacol. 2015. PMID: 26180047

2

Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed.

Rohde LA, Ahring PK, Jensen ML, Nielsen EØ, Peters D, Helgstrand C, Krintel C, Harpsøe K, Gajhede M, Kastrup JS, Balle T. Rohde LA, et al. Among authors: krintel c. J Biol Chem. 2012 Feb 3;287(6):4248-59. doi: 10.1074/jbc.M111.292243. Epub 2011 Dec 13. J Biol Chem. 2012. PMID: 22170047 Free PMC article.

3

Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain.

Krintel C, Harpsøe K, Zachariassen LG, Peters D, Frydenvang K, Pickering DS, Gajhede M, Kastrup JS. Krintel C, et al. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1645-52. doi: 10.1107/S0907444913011839. Epub 2013 Aug 15. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23999288

4

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.

Krintel C, Frydenvang K, Ceravalls de Rabassa A, Kaern AM, Gajhede M, Pickering DS, Kastrup JS. Krintel C, et al. FEBS J. 2014 May;281(10):2422-30. doi: 10.1111/febs.12795. Epub 2014 Apr 17. FEBS J. 2014. PMID: 24673938 Free article.

5

Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors.

Szymanska E, Frydenvang K, Pickering DS, Krintel C, Nielsen B, Kooshki A, Zachariassen LG, Olsen L, Kastrup JS, Johansen TN. Szymanska E, et al. Among authors: krintel c. J Med Chem. 2016 Jan 14;59(1):448-61. doi: 10.1021/acs.jmedchem.5b01666. Epub 2015 Dec 22. J Med Chem. 2016. PMID: 26653877

6

Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2.

Krintel C, Frydenvang K, Olsen L, Kristensen MT, de Barrios O, Naur P, Francotte P, Pirotte B, Gajhede M, Kastrup JS. Krintel C, et al. Biochem J. 2012 Jan 1;441(1):173-8. doi: 10.1042/BJ20111221. Biochem J. 2012. PMID: 21895609

7

Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold.

Nørholm AB, Francotte P, Olsen L, Krintel C, Frydenvang K, Goffin E, Challal S, Danober L, Botez-Pop I, Lestage P, Pirotte B, Kastrup JS. Nørholm AB, et al. Among authors: krintel c. J Med Chem. 2013 Nov 14;56(21):8736-45. doi: 10.1021/jm4012092. Epub 2013 Nov 5. J Med Chem. 2013. PMID: 24131202

8

Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2.

Krintel C, Francotte P, Pickering DS, Juknaitė L, Pøhlsgaard J, Olsen L, Frydenvang K, Goffin E, Pirotte B, Kastrup JS. Krintel C, et al. Biophys J. 2016 Jun 7;110(11):2397-2406. doi: 10.1016/j.bpj.2016.04.032. Biophys J. 2016. PMID: 27276258 Free PMC article.

9

Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2.

Krintel C, Dorosz J, Larsen AH, Thorsen TS, Venskutonytė R, Mirza O, Gajhede M, Boesen T, Kastrup JS. Krintel C, et al. FEBS J. 2021 Feb;288(3):995-1007. doi: 10.1111/febs.15455. Epub 2020 Jul 8. FEBS J. 2021. PMID: 32543078 Free article.

10

Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.

Midtgaard SR, Darwish TA, Pedersen MC, Huda P, Larsen AH, Jensen GV, Kynde SAR, Skar-Gislinge N, Nielsen AJZ, Olesen C, Blaise M, Dorosz JJ, Thorsen TS, Venskutonytė R, Krintel C, Møller JV, Frielinghaus H, Gilbert EP, Martel A, Kastrup JS, Jensen PE, Nissen P, Arleth L. Midtgaard SR, et al. Among authors: krintel c. FEBS J. 2018 Jan;285(2):357-371. doi: 10.1111/febs.14345. Epub 2017 Dec 30. FEBS J. 2018. PMID: 29178440 Free article.

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