Wang C - Search Results

1

Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer.

Zhang Y, Seigal BA, Terrett NK, Talbott RL, Fargnoli J, Naglich JG, Chaudhry C, Posy SL, Vuppugalla R, Cornelius G, Lei M, Wang C, Zhang Y, Schmidt RJ, Wei DD, Miller MM, Allen MP, Li L, Carter PH, Vite GD, Borzilleri RM. Zhang Y, et al. Among authors: wang c. ACS Med Chem Lett. 2015 May 27;6(7):770-5. doi: 10.1021/acsmedchemlett.5b00091. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191364 Free PMC article.

2

Effects of column back pressure on supercritical fluid chromatography separations of enantiomers using binary mobile phases on 10 chiral stationary phases.

Wang C, Zhang Y. Wang C, et al. J Chromatogr A. 2013 Mar 15;1281:127-34. doi: 10.1016/j.chroma.2013.01.050. Epub 2013 Jan 17. J Chromatogr A. 2013. PMID: 23394748

3

Optimization and simulation of tandem column supercritical fluid chromatography separations using column back pressure as a unique parameter.

Wang C, Tymiak AA, Zhang Y. Wang C, et al. Anal Chem. 2014 Apr 15;86(8):4033-40. doi: 10.1021/ac500530n. Epub 2014 Apr 2. Anal Chem. 2014. PMID: 24661124

4

Characterization and quantification of histidine degradation in therapeutic protein formulations by size exclusion-hydrophilic interaction two dimensional-liquid chromatography with stable-isotope labeling mass spectrometry.

Wang C, Chen S, Brailsford JA, Yamniuk AP, Tymiak AA, Zhang Y. Wang C, et al. J Chromatogr A. 2015 Dec 24;1426:133-9. doi: 10.1016/j.chroma.2015.11.065. Epub 2015 Nov 23. J Chromatogr A. 2015. PMID: 26674608

5

Chromatography-based methods for determining molar extinction coefficients of cytotoxic payload drugs and drug antibody ratios of antibody drug conjugates.

Wang C, Chen S, Caceres-Cortes J, Huang RY, Tymiak AA, Zhang Y. Wang C, et al. J Chromatogr A. 2016 Jul 15;1455:133-139. doi: 10.1016/j.chroma.2016.05.086. Epub 2016 May 26. J Chromatogr A. 2016. PMID: 27286648

6

Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers.

Watterson SH, De Lucca GV, Shi Q, Langevine CM, Liu Q, Batt DG, Beaudoin Bertrand M, Gong H, Dai J, Yip S, Li P, Sun D, Wu DR, Wang C, Zhang Y, Traeger SC, Pattoli MA, Skala S, Cheng L, Obermeier MT, Vickery R, Discenza LN, D'Arienzo CJ, Zhang Y, Heimrich E, Gillooly KM, Taylor TL, Pulicicchio C, McIntyre KW, Galella MA, Tebben AJ, Muckelbauer JK, Chang C, Rampulla R, Mathur A, Salter-Cid L, Barrish JC, Carter PH, Fura A, Burke JR, Tino JA. Watterson SH, et al. Among authors: wang c. J Med Chem. 2016 Oct 13;59(19):9173-9200. doi: 10.1021/acs.jmedchem.6b01088. Epub 2016 Sep 19. J Med Chem. 2016. PMID: 27583770

7

Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK.

Srivastava AS, Ko S, Watterson SH, Pattoli MA, Skala S, Cheng L, Obermeier MT, Vickery R, Discenza LN, D'Arienzo CJ, Gillooly KM, Taylor TL, Pulicicchio C, McIntyre KW, Yip S, Li P, Sun D, Wu DR, Dai J, Wang C, Zhang Y, Wang B, Pawluczyk J, Kempson J, Zhao R, Hou X, Rampulla R, Mathur A, Galella MA, Salter-Cid L, Barrish JC, Carter PH, Fura A, Burke JR, Tino JA. Srivastava AS, et al. Among authors: wang c, wang b. ACS Med Chem Lett. 2020 Sep 16;11(11):2195-2203. doi: 10.1021/acsmedchemlett.0c00335. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214829 Free PMC article.

8

Investigation of a Degradant in a Biologics Formulation Buffer Containing L-Histidine.

Wang C, Yamniuk A, Dai J, Chen S, Stetsko P, Ditto N, Zhang Y. Wang C, et al. Pharm Res. 2015 Aug;32(8):2625-35. doi: 10.1007/s11095-015-1648-8. Epub 2015 Feb 12. Pharm Res. 2015. PMID: 25670525

9

Pre-absorption physicochemical compatibility assessment of 8-drug metabolic cocktail.

Tye CK, Wang Z, Dockens RC, Vakkalagadda B, Wang C, Zhang Y, Su CC, Hageman MJ. Tye CK, et al. Among authors: wang z, wang c. Int J Pharm. 2016 Dec 5;514(2):364-373. doi: 10.1016/j.ijpharm.2016.06.028. Epub 2016 Jun 9. Int J Pharm. 2016. PMID: 27291974

10

The role of chromatographic and chiroptical spectroscopic techniques and methodologies in support of drug discovery for atropisomeric drug inhibitors of Bruton's tyrosine kinase.

Dai J, Wang C, Traeger SC, Discenza L, Obermeier MT, Tymiak AA, Zhang Y. Dai J, et al. Among authors: wang c. J Chromatogr A. 2017 Mar 3;1487:116-128. doi: 10.1016/j.chroma.2017.01.016. Epub 2017 Jan 6. J Chromatogr A. 2017. PMID: 28131592

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