A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults.
Gotthardt D, Runz H, Keitel V, Fischer C, Flechtenmacher C, Wirtenberger M, Weiss KH, Imparato S, Braun A, Hemminki K, Stremmel W, Rüschendorf F, Stiehl A, Kubitz R, Burwinkel B, Schirmacher P, Knisely AS, Zschocke J, Sauer P.
Gotthardt D, et al. Among authors: schirmacher p.
Hepatology. 2008 Oct;48(4):1157-66. doi: 10.1002/hep.22485.
Hepatology. 2008.
PMID: 18781607