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Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer.
Rautela J, Baschuk N, Slaney CY, Jayatilleke KM, Xiao K, Bidwell BN, Lucas EC, Hawkins ED, Lock P, Wong CS, Chen W, Anderson RL, Hertzog PJ, Andrews DM, Möller A, Parker BS. Rautela J, et al. Among authors: lock p. Cancer Immunol Res. 2015 Nov;3(11):1207-17. doi: 10.1158/2326-6066.CIR-15-0065. Epub 2015 Jul 21. Cancer Immunol Res. 2015. PMID: 26198985
Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer.
Konda SK, Maliki R, McGrath S, Parker BS, Robinson T, Spurling A, Cheong A, Lock P, Pigram PJ, Phillips DR, Wallace L, Day AI, Collins JG, Cutts SM. Konda SK, et al. Among authors: lock p. ACS Med Chem Lett. 2017 Apr 24;8(5):538-542. doi: 10.1021/acsmedchemlett.7b00090. eCollection 2017 May 11. ACS Med Chem Lett. 2017. PMID: 28523107 Free PMC article.
FGF13 promotes metastasis of triple-negative breast cancer.
Johnstone CN, Pattison AD, Harrison PF, Powell DR, Lock P, Ernst M, Anderson RL, Beilharz TH. Johnstone CN, et al. Among authors: lock p. Int J Cancer. 2020 Jul 1;147(1):230-243. doi: 10.1002/ijc.32874. Epub 2020 Feb 24. Int J Cancer. 2020. PMID: 31957002
A switch in mechanism of action prevents doxorubicin-mediated cardiac damage.
Cheong A, McGrath S, Robinson T, Maliki R, Spurling A, Lock P, Rephaeli A, Nudelman A, Parker BS, Pepe S, Cutts SM. Cheong A, et al. Among authors: lock p. Biochem Pharmacol. 2021 Mar;185:114410. doi: 10.1016/j.bcp.2021.114410. Epub 2021 Jan 9. Biochem Pharmacol. 2021. PMID: 33428897
86 results