Penn RB - Search Results

1

Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response.

Chan TO, Zhang J, Tiegs BC, Blumhof B, Yan L, Keny N, Penny M, Li X, Pascal JM, Armen RS, Rodeck U, Penn RB. Chan TO, et al. Among authors: penn rb. Biochem J. 2015 Oct 1;471(1):37-51. doi: 10.1042/BJ20150325. Epub 2015 Jul 22. Biochem J. 2015. PMID: 26201515 Free PMC article.

2

Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth.

Billington CK, Kong KC, Bhattacharyya R, Wedegaertner PB, Panettieri RA Jr, Chan TO, Penn RB. Billington CK, et al. Among authors: penn rb. Biochemistry. 2005 Nov 8;44(44):14595-605. doi: 10.1021/bi0510734. Biochemistry. 2005. PMID: 16262259

3

Deletion of the pH sensor GPR4 decreases renal acid excretion.

Sun X, Yang LV, Tiegs BC, Arend LJ, McGraw DW, Penn RB, Petrovic S. Sun X, et al. Among authors: penn rb. J Am Soc Nephrol. 2010 Oct;21(10):1745-55. doi: 10.1681/ASN.2009050477. Epub 2010 Aug 26. J Am Soc Nephrol. 2010. PMID: 20798260 Free PMC article.

4

Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle.

Deshpande DA, Yan H, Kong KC, Tiegs BC, Morgan SJ, Pera T, Panettieri RA, Eckhart AD, Penn RB. Deshpande DA, et al. Among authors: penn rb. FASEB J. 2014 Feb;28(2):956-65. doi: 10.1096/fj.13-240226. Epub 2013 Oct 16. FASEB J. 2014. PMID: 24132623 Free PMC article.

5

β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent.

Morgan SJ, Deshpande DA, Tiegs BC, Misior AM, Yan H, Hershfeld AV, Rich TC, Panettieri RA, An SS, Penn RB. Morgan SJ, et al. Among authors: penn rb. J Biol Chem. 2014 Aug 15;289(33):23065-23074. doi: 10.1074/jbc.M114.557652. Epub 2014 Jun 27. J Biol Chem. 2014. PMID: 24973219 Free PMC article.

6

Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function.

Pera T, Hegde A, Deshpande DA, Morgan SJ, Tiegs BC, Theriot BS, Choi YH, Walker JK, Penn RB. Pera T, et al. Among authors: penn rb. FASEB J. 2015 Oct;29(10):4227-35. doi: 10.1096/fj.15-273094. Epub 2015 Jun 23. FASEB J. 2015. PMID: 26103985 Free PMC article.

7

A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation.

Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB. Chan TO, et al. Among authors: penn rb. J Biol Chem. 2020 Mar 6;295(10):3316-3329. doi: 10.1074/jbc.RA119.010004. Epub 2020 Jan 21. J Biol Chem. 2020. PMID: 31964716 Free PMC article.

8

Identification of a β-arrestin-biased negative allosteric modulator for the β₂-adrenergic receptor.

Ippolito M, De Pascali F, Hopfinger N, Komolov KE, Laurinavichyute D, Reddy PAN, Sakkal LA, Rajkowski KZ, Nayak AP, Lee J, Lee J, Cao G, Donover PS, Reichman M, An SS, Salvino JM, Penn RB, Armen RS, Scott CP, Benovic JL. Ippolito M, et al. Among authors: penn rb. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2302668120. doi: 10.1073/pnas.2302668120. Epub 2023 Jul 25. Proc Natl Acad Sci U S A. 2023. PMID: 37490535 Free PMC article.

9

MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation.

Orsini MJ, Krymskaya VP, Eszterhas AJ, Benovic JL, Panettieri RA Jr, Penn RB. Orsini MJ, et al. Among authors: penn rb. Am J Physiol. 1999 Sep;277(3):L479-88. doi: 10.1152/ajplung.1999.277.3.L479. Am J Physiol. 1999. PMID: 10484455

10

The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH.

Saxena H, Deshpande DA, Tiegs BC, Yan H, Battafarano RJ, Burrows WM, Damera G, Panettieri RA, Dubose TD Jr, An SS, Penn RB. Saxena H, et al. Among authors: penn rb. Br J Pharmacol. 2012 Jun;166(3):981-90. doi: 10.1111/j.1476-5381.2011.01807.x. Br J Pharmacol. 2012. PMID: 22145625 Free PMC article.

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