Kopczynski CC - Search Results

1

Fixed-dose combination of AR-13324 and latanoprost: a double-masked, 28-day, randomised, controlled study in patients with open-angle glaucoma or ocular hypertension.

Lewis RA, Levy B, Ramirez N, Kopczynski CC, Usner DW, Novack GD; PG324-CS201 Study Group. Lewis RA, et al. Among authors: kopczynski cc. Br J Ophthalmol. 2016 Mar;100(3):339-44. doi: 10.1136/bjophthalmol-2015-306778. Epub 2015 Jul 24. Br J Ophthalmol. 2016. PMID: 26209587 Clinical Trial.

2

Ocular hypotensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension.

Williams RD, Novack GD, van Haarlem T, Kopczynski C; AR-12286 Phase 2A Study Group. Williams RD, et al. Am J Ophthalmol. 2011 Nov;152(5):834-41.e1. doi: 10.1016/j.ajo.2011.04.012. Epub 2011 Jul 27. Am J Ophthalmol. 2011. PMID: 21794845 Clinical Trial.

3

Ocular hypotensive efficacy, safety and systemic absorption of AR-12286 ophthalmic solution in normal volunteers.

Kopczynski C, Novack GD, Swearingen D, van Haarlem T. Kopczynski C, et al. Br J Ophthalmol. 2013 May;97(5):567-72. doi: 10.1136/bjophthalmol-2012-302466. Epub 2013 Feb 22. Br J Ophthalmol. 2013. PMID: 23435190 Clinical Trial.

4

Double-masked, randomized, dose-response study of AR-13324 versus latanoprost in patients with elevated intraocular pressure.

Bacharach J, Dubiner HB, Levy B, Kopczynski CC, Novack GD; AR-13324-CS202 Study Group. Bacharach J, et al. Among authors: kopczynski cc. Ophthalmology. 2015 Feb;122(2):302-7. doi: 10.1016/j.ophtha.2014.08.022. Epub 2014 Sep 27. Ophthalmology. 2015. PMID: 25270273 Clinical Trial.

5

Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes.

Wang RF, Williamson JE, Kopczynski C, Serle JB. Wang RF, et al. J Glaucoma. 2015 Jan;24(1):51-4. doi: 10.1097/IJG.0b013e3182952213. J Glaucoma. 2015. PMID: 25535688

6

Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers.

Levy B, Ramirez N, Novack GD, Kopczynski C. Levy B, et al. Am J Ophthalmol. 2015 May;159(5):980-5.e1. doi: 10.1016/j.ajo.2015.01.026. Epub 2015 Jan 28. Am J Ophthalmol. 2015. PMID: 25637177 Clinical Trial.

7

Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits.

Kiel JW, Kopczynski CC. Kiel JW, et al. Among authors: kopczynski cc. J Ocul Pharmacol Ther. 2015 Apr;31(3):146-51. doi: 10.1089/jop.2014.0146. Epub 2015 Mar 10. J Ocul Pharmacol Ther. 2015. PMID: 25756366 Free PMC article.

8

Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma.

Sturdivant JM, Royalty SM, Lin CW, Moore LA, Yingling JD, Laethem CL, Sherman B, Heintzelman GR, Kopczynski CC, deLong MA. Sturdivant JM, et al. Among authors: kopczynski cc. Bioorg Med Chem Lett. 2016 May 15;26(10):2475-2480. doi: 10.1016/j.bmcl.2016.03.104. Epub 2016 Apr 1. Bioorg Med Chem Lett. 2016. PMID: 27072905

9

Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms.

Ren R, Li G, Le TD, Kopczynski C, Stamer WD, Gong H. Ren R, et al. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6197-6209. doi: 10.1167/iovs.16-20189. Invest Ophthalmol Vis Sci. 2016. PMID: 27842161 Free PMC article.

10

Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma.

Lin CW, Sherman B, Moore LA, Laethem CL, Lu DW, Pattabiraman PP, Rao PV, deLong MA, Kopczynski CC. Lin CW, et al. Among authors: kopczynski cc. J Ocul Pharmacol Ther. 2018 Jan/Feb;34(1-2):40-51. doi: 10.1089/jop.2017.0023. Epub 2017 Jun 13. J Ocul Pharmacol Ther. 2018. PMID: 28609185 Free PMC article.

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