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Mena binds α5 integrin directly and modulates α5β1 function.
Gupton SL, Riquelme D, Hughes-Alford SK, Tadros J, Rudina SS, Hynes RO, Lauffenburger D, Gertler FB. Gupton SL, et al. J Cell Biol. 2012 Aug 20;198(4):657-76. doi: 10.1083/jcb.201202079. J Cell Biol. 2012. PMID: 22908313 Free PMC article.
Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.
Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, Lauffenburger DA, Keely PJ, Bear JE, Gertler FB. Oudin MJ, et al. Cancer Discov. 2016 May;6(5):516-31. doi: 10.1158/2159-8290.CD-15-1183. Epub 2016 Jan 25. Cancer Discov. 2016. PMID: 26811325 Free PMC article.