Shimizu M - Search Results

1

Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.

Uehara S, Uno Y, Inoue T, Kawano M, Shimizu M, Toda A, Utoh M, Sasaki E, Yamazaki H. Uehara S, et al. Among authors: shimizu m. Drug Metab Dispos. 2015 Oct;43(10):1408-16. doi: 10.1124/dmd.115.066100. Epub 2015 Jul 30. Drug Metab Dispos. 2015. PMID: 26228688

2

Activities of rat cytochrome P450 3A and 2C isoforms are increased in vivo by magnesium sulfate as evidenced by enhanced oxidation of bupivacaine and testosterone in liver microsomes.

Saito M, Okutomi T, Shimizu M, Matsumoto Y, Yamazaki H, Hoka S. Saito M, et al. Among authors: shimizu m. Drug Metab Pharmacokinet. 2006 Jun;21(3):201-7. doi: 10.2133/dmpk.21.201. Drug Metab Pharmacokinet. 2006. PMID: 16858123 Free article.

3

Three novel single nucleotide polymorphisms of the FMO3 gene in a Japanese population.

Shimizu M, Fujita H, Aoyama T, Yamazaki H. Shimizu M, et al. Drug Metab Pharmacokinet. 2006 Jun;21(3):245-7. doi: 10.2133/dmpk.21.245. Drug Metab Pharmacokinet. 2006. PMID: 16858129 Free article.

4

Rat cytochrome P450 2C11 in liver microsomes involved in oxidation of anesthetic agent propofol and deactivated by prior treatment with propofol.

Yamazaki H, Shimizu M, Nagashima T, Minoshima M, Murayama N. Yamazaki H, et al. Among authors: shimizu m. Drug Metab Dispos. 2006 Nov;34(11):1803-5. doi: 10.1124/dmd.106.011627. Epub 2006 Aug 8. Drug Metab Dispos. 2006. PMID: 16896062

5

Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.

Yamazaki H, Fujita H, Gunji T, Zhang J, Kamataki T, Cashman JR, Shimizu M. Yamazaki H, et al. Among authors: shimizu m. Mol Genet Metab. 2007 Jan;90(1):58-63. doi: 10.1016/j.ymgme.2006.08.008. Epub 2006 Sep 25. Mol Genet Metab. 2007. PMID: 16996766

6

High-performance liquid chromatographic assay for carboplatin in ultrafiltered plasma combined with hyperbaric oxygenation.

Yamazaki H, Tanaka K, Gamura S, Hashimoto T, Shimizu M. Yamazaki H, et al. Among authors: shimizu m. Drug Metab Pharmacokinet. 2006 Oct;21(5):429-31. doi: 10.2133/dmpk.21.429. Drug Metab Pharmacokinet. 2006. PMID: 17072097 Free article.

7

Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities.

Shimizu M, Yano H, Nagashima S, Murayama N, Zhang J, Cashman JR, Yamazaki H. Shimizu M, et al. Drug Metab Dispos. 2007 Mar;35(3):328-30. doi: 10.1124/dmd.106.013094. Epub 2006 Dec 1. Drug Metab Dispos. 2007. PMID: 17142560

8

Transient trimethylaminuria related to menstruation.

Shimizu M, Cashman JR, Yamazaki H. Shimizu M, et al. BMC Med Genet. 2007 Jan 27;8:2. doi: 10.1186/1471-2350-8-2. BMC Med Genet. 2007. PMID: 17257434 Free PMC article.

9

Missense and nonsense mutations of the flavin-containing monooxygenase 3 gene in a Japanese cohort.

Shimizu M, Tomioka S, Murayama N, Yamazaki H. Shimizu M, et al. Drug Metab Pharmacokinet. 2007 Feb 25;22(1):61-4. doi: 10.2133/dmpk.22.61. Drug Metab Pharmacokinet. 2007. PMID: 17329912 Free article.

10

Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.

Murayama N, Imai N, Nakane T, Shimizu M, Yamazaki H. Murayama N, et al. Among authors: shimizu m. Biochem Pharmacol. 2007 Jun 15;73(12):2020-6. doi: 10.1016/j.bcp.2007.03.012. Epub 2007 Mar 19. Biochem Pharmacol. 2007. PMID: 17433262

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