Davenport R - Search Results

1

Selective FFA2 Agonism Appears to Act via Intestinal PYY to Reduce Transit and Food Intake but Does Not Improve Glucose Tolerance in Mouse Models.

Forbes S, Stafford S, Coope G, Heffron H, Real K, Newman R, Davenport R, Barnes M, Grosse J, Cox H. Forbes S, et al. Among authors: davenport r. Diabetes. 2015 Nov;64(11):3763-71. doi: 10.2337/db15-0481. Epub 2015 Aug 3. Diabetes. 2015. PMID: 26239054

2

Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing.

Sakurai T, Davenport R, Stafford S, Grosse J, Ogawa K, Cameron J, Parton L, Sykes A, Mack S, Bousba S, Parmar A, Harrison D, Dickson L, Leveridge M, Matsui J, Barnes M. Sakurai T, et al. Among authors: davenport r. Eur J Pharmacol. 2014 Mar 15;727:1-7. doi: 10.1016/j.ejphar.2014.01.029. Epub 2014 Jan 30. Eur J Pharmacol. 2014. PMID: 24486398

3

Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).

Hendrick AG, Müller I, Willems H, Leonard PM, Irving S, Davenport R, Ito T, Reeves J, Wright S, Allen V, Wilkinson S, Heffron H, Bazin R, Turney J, Mitchell PJ. Hendrick AG, et al. Among authors: davenport r. J Med Chem. 2016 Sep 8;59(17):8094-102. doi: 10.1021/acs.jmedchem.6b00869. Epub 2016 Aug 18. J Med Chem. 2016. PMID: 27500412

4

Treating obesity: is it all in the gut?

Davenport RJ, Wright S. Davenport RJ, et al. Drug Discov Today. 2014 Jul;19(7):845-58. doi: 10.1016/j.drudis.2013.10.025. Epub 2013 Nov 27. Drug Discov Today. 2014. PMID: 24291217 Review.

5

Synthesis and structure-activity relationships of guanine analogues as phosphodiesterase 7 (PDE7) inhibitors.

Barnes MJ, Cooper N, Davenport RJ, Dyke HJ, Galleway FP, Galvin FC, Gowers L, Haughan AF, Lowe C, Meissner JW, Montana JG, Morgan T, Picken CL, Watson RJ. Barnes MJ, et al. Among authors: davenport rj. Bioorg Med Chem Lett. 2001 Apr 23;11(8):1081-3. doi: 10.1016/s0960-894x(01)00125-1. Bioorg Med Chem Lett. 2001. PMID: 11327595

6

A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT).

Lanier M, Ambrus G, Cole DC, Davenport R, Ellery J, Fosbeary R, Jennings AJ, Kadotani A, Kamada Y, Kamran R, Matsumoto S, Mizukami A, Okubo S, Okada K, Saikatendu K, Walsh L, Wu H, Hixon MS. Lanier M, et al. Among authors: davenport r. J Med Chem. 2014 Jun 26;57(12):5459-63. doi: 10.1021/jm500475k. Epub 2014 Jun 4. J Med Chem. 2014. PMID: 24847974

7

1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction.

Ahmed S, Ayscough A, Barker GR, Canning HE, Davenport R, Downham R, Harrison D, Jenkins K, Kinsella N, Livermore DG, Wright S, Ivetac AD, Skene R, Wilkens SJ, Webster NA, Hendrick AG. Ahmed S, et al. Among authors: davenport r. J Med Chem. 2017 Jul 13;60(13):5663-5672. doi: 10.1021/acs.jmedchem.7b00352. Epub 2017 Jun 24. J Med Chem. 2017. PMID: 28594552

8

Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases?

Davenport RJ, Munday JR. Davenport RJ, et al. Drug Discov Today. 2007 Jul;12(13-14):569-76. doi: 10.1016/j.drudis.2007.05.001. Epub 2007 Jun 26. Drug Discov Today. 2007. PMID: 17631252 Review.

9

7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma.

Buckley GM, Cooper N, Davenport RJ, Dyke HJ, Galleway FP, Gowers L, Haughan AF, Kendall HJ, Lowe C, Montana JG, Oxford J, Peake JC, Picken CL, Richard MD, Sabin V, Sharpe A, Warneck JB. Buckley GM, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):509-12. doi: 10.1016/s0960-894x(01)00786-7. Bioorg Med Chem Lett. 2002. PMID: 11814830

10

A novel series of potent and selective IKK2 inhibitors.

Bingham AH, Davenport RJ, Gowers L, Knight RL, Lowe C, Owen DA, Parry DM, Pitt WR. Bingham AH, et al. Among authors: davenport rj. Bioorg Med Chem Lett. 2004 Jan 19;14(2):409-12. doi: 10.1016/j.bmcl.2003.10.047. Bioorg Med Chem Lett. 2004. PMID: 14698170

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