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Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation.
Lutz ER, Wu AA, Bigelow E, Sharma R, Mo G, Soares K, Solt S, Dorman A, Wamwea A, Yager A, Laheru D, Wolfgang CL, Wang J, Hruban RH, Anders RA, Jaffee EM, Zheng L. Lutz ER, et al. Among authors: wu aa. Cancer Immunol Res. 2014 Jul;2(7):616-31. doi: 10.1158/2326-6066.CIR-14-0027. Epub 2014 Jun 18. Cancer Immunol Res. 2014. PMID: 24942756 Free PMC article. Clinical Trial.
Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer.
Kinkead HL, Hopkins A, Lutz E, Wu AA, Yarchoan M, Cruz K, Woolman S, Vithayathil T, Glickman LH, Ndubaku CO, McWhirter SM, Dubensky TW Jr, Armstrong TD, Jaffee EM, Zaidi N. Kinkead HL, et al. Among authors: wu aa. JCI Insight. 2018 Oct 18;3(20):e122857. doi: 10.1172/jci.insight.122857. JCI Insight. 2018. PMID: 30333318 Free PMC article.
Evaluation of Cyclophosphamide/GVAX Pancreas Followed by Listeria-Mesothelin (CRS-207) with or without Nivolumab in Patients with Pancreatic Cancer.
Tsujikawa T, Crocenzi T, Durham JN, Sugar EA, Wu AA, Onners B, Nauroth JM, Anders RA, Fertig EJ, Laheru DA, Reiss K, Vonderheide RH, Ko AH, Tempero MA, Fisher GA, Considine M, Danilova L, Brockstedt DG, Coussens LM, Jaffee EM, Le DT. Tsujikawa T, et al. Among authors: wu aa. Clin Cancer Res. 2020 Jul 15;26(14):3578-3588. doi: 10.1158/1078-0432.CCR-19-3978. Epub 2020 Apr 9. Clin Cancer Res. 2020. PMID: 32273276 Free PMC article. Clinical Trial.
An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma.
Bever KM, Borazanci EH, Thompson EA, Durham JN, Pinero K, Jameson GS, Vrana A, Liu M, Wilt C, Wu AA, Fu W, Wang H, Yin Y, Leal JP, Jesus-Acosta A, Zheng L, Laheru DA, Von Hoff DD, Jaffee EM, Powell JD, Le DT. Bever KM, et al. Among authors: wu aa. Oncotarget. 2020 May 26;11(21):1929-1941. doi: 10.18632/oncotarget.27586. eCollection 2020 May 26. Oncotarget. 2020. PMID: 32523648 Free PMC article.
46 results