Chen A - Search Results

1

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection.

Chen A, Mann B, Gao G, Heath R, King J, Maissoneuve J, Alderson M, Tate A, Hollingshead SK, Tweten RK, Briles DE, Tuomanen EI, Paton JC. Chen A, et al. Clin Vaccine Immunol. 2015 Oct;22(10):1079-89. doi: 10.1128/CVI.00293-15. Epub 2015 Aug 5. Clin Vaccine Immunol. 2015. PMID: 26245351 Free PMC article.

2

Intranasal vaccination with γ-irradiated Streptococcus pneumoniae whole-cell vaccine provides serotype-independent protection mediated by B-cells and innate IL-17 responses.

Babb R, Chen A, Hirst TR, Kara EE, McColl SR, Ogunniyi AD, Paton JC, Alsharifi M. Babb R, et al. Among authors: chen a. Clin Sci (Lond). 2016 May;130(9):697-710. doi: 10.1042/CS20150699. Epub 2016 Feb 1. Clin Sci (Lond). 2016. PMID: 26831937

3

Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine.

Babb R, Chen A, Ogunniyi AD, Hirst TR, Kara EE, McColl SR, Alsharifi M, Paton JC. Babb R, et al. Among authors: chen a. Clin Sci (Lond). 2017 Jan 1;131(2):169-180. doi: 10.1042/CS20160475. Epub 2016 Nov 24. Clin Sci (Lond). 2017. PMID: 27885052

4

Pneumolysin with low hemolytic activity confers an early growth advantage to Streptococcus pneumoniae in the blood.

Harvey RM, Ogunniyi AD, Chen AY, Paton JC. Harvey RM, et al. Infect Immun. 2011 Oct;79(10):4122-30. doi: 10.1128/IAI.05418-11. Epub 2011 Jul 25. Infect Immun. 2011. PMID: 21788389 Free PMC article.

5

Enhanced safety and immunogenicity of a pneumococcal surface antigen A mutant whole-cell inactivated pneumococcal vaccine.

David SC, Laan Z, Minhas V, Chen AY, Davies J, Hirst TR, McColl SR, Alsharifi M, Paton JC. David SC, et al. Immunol Cell Biol. 2019 Sep;97(8):726-739. doi: 10.1111/imcb.12257. Epub 2019 May 23. Immunol Cell Biol. 2019. PMID: 31050022

6

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence.

Trappetti C, McAllister LJ, Chen A, Wang H, Paton AW, Oggioni MR, McDevitt CA, Paton JC. Trappetti C, et al. Among authors: chen a. mBio. 2017 Jan 24;8(1):e02269-16. doi: 10.1128/mBio.02269-16. mBio. 2017. PMID: 28119473 Free PMC article.

7

Site of isolation determines biofilm formation and virulence phenotypes of Streptococcus pneumoniae serotype 3 clinical isolates.

Trappetti C, van der Maten E, Amin Z, Potter AJ, Chen AY, van Mourik PM, Lawrence AJ, Paton AW, Paton JC. Trappetti C, et al. Infect Immun. 2013 Feb;81(2):505-13. doi: 10.1128/IAI.01033-12. Epub 2012 Dec 3. Infect Immun. 2013. PMID: 23208608 Free PMC article.

8

Protection against Shiga-Toxigenic Escherichia coli by Non-Genetically Modified Organism Receptor Mimic Bacterial Ghosts.

Paton AW, Chen AY, Wang H, McAllister LJ, Höggerl F, Mayr UB, Shewell LK, Jennings MP, Morona R, Lubitz W, Paton JC. Paton AW, et al. Infect Immun. 2015 Sep;83(9):3526-33. doi: 10.1128/IAI.00669-15. Epub 2015 Jun 22. Infect Immun. 2015. PMID: 26099582 Free PMC article.

9

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.

Shewell LK, Harvey RM, Higgins MA, Day CJ, Hartley-Tassell LE, Chen AY, Gillen CM, James DB, Alonzo F 3rd, Torres VJ, Walker MJ, Paton AW, Paton JC, Jennings MP. Shewell LK, et al. Among authors: chen ay. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5312-20. doi: 10.1073/pnas.1412703111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422425 Free PMC article.

10

A Nonadjuvanted Whole-Inactivated Pneumococcal Vaccine Induces Multiserotype Opsonophagocytic Responses Mediated by Noncapsule-Specific Antibodies.

David SC, Brazel EB, Singleton EV, Minhas V, Laan Z, Scougall C, Chen AY, Wang H, Gates CJ, McLean KT, Brown JS, Ercoli G, Higgins RA, Licciardi PV, Mulholland K, Davies JB, Hirst TR, Paton JC, Alsharifi M. David SC, et al. Among authors: chen ay. mBio. 2022 Oct 26;13(5):e0236722. doi: 10.1128/mbio.02367-22. Epub 2022 Sep 20. mBio. 2022. PMID: 36125268 Free PMC article.

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