Littler D - Search Results

1

Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries).

Sakthivel D, Littler D, Shahine A, Troy S, Johnson M, Rossjohn J, Piedrafita D, Beddoe T. Sakthivel D, et al. Among authors: littler d. Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):993-7. doi: 10.1107/S2053230X15010195. Epub 2015 Jul 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26249688 Free PMC article.

2

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.

Luna-Vargas MP, Christodoulou E, Alfieri A, van Dijk WJ, Stadnik M, Hibbert RG, Sahtoe DD, Clerici M, Marco VD, Littler D, Celie PH, Sixma TK, Perrakis A. Luna-Vargas MP, et al. Among authors: littler d. J Struct Biol. 2011 Aug;175(2):113-9. doi: 10.1016/j.jsb.2011.03.017. Epub 2011 Mar 29. J Struct Biol. 2011. PMID: 21453775

3

Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages.

Shahine AE, Chan PY, Littler D, Vivian J, Brammananth R, Crellin PK, Coppel RL, Rossjohn J, Beddoe T. Shahine AE, et al. Among authors: littler d. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1;69(Pt 5):566-9. doi: 10.1107/S1744309113010427. Epub 2013 Apr 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23695579 Free PMC article.

4

Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB₅ toxin.

Ng N, Littler D, Le Nours J, Paton AW, Paton JC, Rossjohn J, Beddoe T. Ng N, et al. Among authors: littler d. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):912-5. doi: 10.1107/S1744309113018927. Epub 2013 Jul 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23908042 Free PMC article.

5

EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit.

Ng NM, Littler DR, Paton AW, Le Nours J, Rossjohn J, Paton JC, Beddoe T. Ng NM, et al. Structure. 2013 Nov 5;21(11):2003-13. doi: 10.1016/j.str.2013.08.024. Epub 2013 Oct 3. Structure. 2013. PMID: 24095060 Free article.

6

The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins.

Berry R, Vivian JP, Deuss FA, Balaji GR, Saunders PM, Lin J, Littler DR, Brooks AG, Rossjohn J. Berry R, et al. J Biol Chem. 2014 Aug 22;289(34):23753-63. doi: 10.1074/jbc.M114.584128. Epub 2014 Jun 30. J Biol Chem. 2014. PMID: 24982419 Free PMC article.

7

A structural and functional investigation of a novel protein from Mycobacterium smegmatis implicated in mycobacterial macrophage survivability.

Shahine A, Littler D, Brammananath R, Chan PY, Crellin PK, Coppel RL, Rossjohn J, Beddoe T. Shahine A, et al. Among authors: littler d. Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2264-76. doi: 10.1107/S139900471401092X. Epub 2014 Aug 23. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25195741

8

Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.

Littler DR, Bullen HE, Harvey KL, Beddoe T, Crabb BS, Rossjohn J, Gilson PR. Littler DR, et al. J Biol Chem. 2016 Dec 2;291(49):25375-25386. doi: 10.1074/jbc.M116.750174. Epub 2016 Oct 13. J Biol Chem. 2016. PMID: 27738107 Free PMC article.

9

Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.

Jaafar NR, Littler D, Beddoe T, Rossjohn J, Illias RM, Mahadi NM, Mackeen MM, Murad AM, Abu Bakar FD. Jaafar NR, et al. Among authors: littler d. Acta Crystallogr F Struct Biol Commun. 2016 Nov 1;72(Pt 11):831-839. doi: 10.1107/S2053230X16015612. Epub 2016 Oct 27. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27827354 Free PMC article.

10

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins.

Littler DR, Ang SY, Moriel DG, Kocan M, Kleifeld O, Johnson MD, Tran MT, Paton AW, Paton JC, Summers RJ, Schembri MA, Rossjohn J, Beddoe T. Littler DR, et al. J Biol Chem. 2017 Sep 8;292(36):15143-15158. doi: 10.1074/jbc.M117.796094. Epub 2017 Jun 29. J Biol Chem. 2017. PMID: 28663369 Free PMC article.

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