Pacheco E - Search Results

1

Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats.

Ominsky MS, Brown DL, Van G, Cordover D, Pacheco E, Frazier E, Cherepow L, Higgins-Garn M, Aguirre JI, Wronski TJ, Stolina M, Zhou L, Pyrah I, Boyce RW. Ominsky MS, et al. Among authors: pacheco e. Bone. 2015 Dec;81:380-391. doi: 10.1016/j.bone.2015.08.007. Epub 2015 Aug 8. Bone. 2015. PMID: 26261096 Free article.

2

Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats.

Taylor S, Ominsky MS, Hu R, Pacheco E, He YD, Brown DL, Aguirre JI, Wronski TJ, Buntich S, Afshari CA, Pyrah I, Nioi P, Boyce RW. Taylor S, et al. Among authors: pacheco e. Bone. 2016 Mar;84:148-159. doi: 10.1016/j.bone.2015.12.013. Epub 2015 Dec 22. Bone. 2016. PMID: 26721737 Free article.

3

Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats.

Taylor S, Hu R, Pacheco E, Locher K, Pyrah I, Ominsky MS, Boyce RW. Taylor S, et al. Among authors: pacheco e. Bone Rep. 2018 Mar 15;8:95-103. doi: 10.1016/j.bonr.2018.03.002. eCollection 2018 Jun. Bone Rep. 2018. PMID: 29955627 Free PMC article.

4

Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats.

Nioi P, Taylor S, Hu R, Pacheco E, He YD, Hamadeh H, Paszty C, Pyrah I, Ominsky MS, Boyce RW. Nioi P, et al. Among authors: pacheco e. J Bone Miner Res. 2015 Aug;30(8):1457-67. doi: 10.1002/jbmr.2482. Epub 2015 May 22. J Bone Miner Res. 2015. PMID: 25678055 Free article.

5

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair.

Florio M, Gunasekaran K, Stolina M, Li X, Liu L, Tipton B, Salimi-Moosavi H, Asuncion FJ, Li C, Sun B, Tan HL, Zhang L, Han CY, Case R, Duguay AN, Grisanti M, Stevens J, Pretorius JK, Pacheco E, Jones H, Chen Q, Soriano BD, Wen J, Heron B, Jacobsen FW, Brisan E, Richards WG, Ke HZ, Ominsky MS. Florio M, et al. Among authors: pacheco e. Nat Commun. 2016 May 27;7:11505. doi: 10.1038/ncomms11505. Nat Commun. 2016. PMID: 27230681 Free PMC article.

6

RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies.

Stolina M, Schett G, Dwyer D, Vonderfecht S, Middleton S, Duryea D, Pacheco E, Van G, Bolon B, Feige U, Zack D, Kostenuik P. Stolina M, et al. Among authors: pacheco e. Arthritis Res Ther. 2009;11(6):R187. doi: 10.1186/ar2879. Epub 2009 Dec 11. Arthritis Res Ther. 2009. PMID: 20003323 Free PMC article.

7

Laser Capture Microdissection and Transcriptional Analysis of Sub-Populations of the Osteoblast Lineage from Undecalcified Bone.

Pacheco E, Hu R, Taylor S. Pacheco E, et al. Methods Mol Biol. 2018;1723:191-202. doi: 10.1007/978-1-4939-7558-7_10. Methods Mol Biol. 2018. PMID: 29344861

8

Inhibition of interleukin-1 but not tumor necrosis factor suppresses neovascularization in rat models of corneal angiogenesis and adjuvant arthritis.

Coxon A, Bolon B, Estrada J, Kaufman S, Scully S, Rattan A, Duryea D, Hu YL, Rex K, Pacheco E, Van G, Zack D, Feige U. Coxon A, et al. Among authors: pacheco e. Arthritis Rheum. 2002 Oct;46(10):2604-12. doi: 10.1002/art.10546. Arthritis Rheum. 2002. PMID: 12384918 Free article.

9

Antagonists of CD117 (cKit) signaling inhibit mast cell accumulation in healing skin wounds.

Zoog SJ, Itano A, Trueblood E, Pacheco E, Zhou L, Zhang X, Ferbas J, Ng GY, Juan G. Zoog SJ, et al. Among authors: pacheco e. Cytometry A. 2009 Mar;75(3):189-98. doi: 10.1002/cyto.a.20658. Cytometry A. 2009. PMID: 18937342 Free article.

10

Sclerostin is expressed in articular cartilage but loss or inhibition does not affect cartilage remodeling during aging or following mechanical injury.

Roudier M, Li X, Niu QT, Pacheco E, Pretorius JK, Graham K, Yoon BR, Gong J, Warmington K, Ke HZ, Black RA, Hulme J, Babij P. Roudier M, et al. Among authors: pacheco e. Arthritis Rheum. 2013 Mar;65(3):721-31. doi: 10.1002/art.37802. Arthritis Rheum. 2013. PMID: 23233270 Free article.

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