Davies BR - Search Results

1

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy.

O'Neill D, Jones D, Wade M, Grey J, Nakjang S, Guo W, Cork D, Davies BR, Wedge SR, Robson CN, Gaughan L. O'Neill D, et al. Among authors: davies br. Oncotarget. 2015 Sep 22;6(28):26029-40. doi: 10.18632/oncotarget.4347. Oncotarget. 2015. PMID: 26267320 Free PMC article.

2

High Efficacy of Combination Therapy Using PI3K/AKT Inhibitors with Androgen Deprivation in Prostate Cancer Preclinical Models.

Marques RB, Aghai A, de Ridder CMA, Stuurman D, Hoeben S, Boer A, Ellston RP, Barry ST, Davies BR, Trapman J, van Weerden WM. Marques RB, et al. Among authors: davies br. Eur Urol. 2015 Jun;67(6):1177-1185. doi: 10.1016/j.eururo.2014.08.053. Epub 2014 Sep 12. Eur Urol. 2015. PMID: 25220373

3

Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma.

Ezell SA, Wang S, Bihani T, Lai Z, Grosskurth SE, Tepsuporn S, Davies BR, Huszar D, Byth KF. Ezell SA, et al. Among authors: davies br. Oncotarget. 2016 Feb 23;7(8):9163-74. doi: 10.18632/oncotarget.7036. Oncotarget. 2016. PMID: 26824321 Free PMC article.

4

Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTEN-deficient prostate cancer.

De Velasco MA, Kura Y, Yoshikawa K, Nishio K, Davies BR, Uemura H. De Velasco MA, et al. Among authors: davies br. Oncotarget. 2016 Mar 29;7(13):15959-76. doi: 10.18632/oncotarget.7557. Oncotarget. 2016. PMID: 26910118 Free PMC article.

5

Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen.

Lynch JT, McEwen R, Crafter C, McDermott U, Garnett MJ, Barry ST, Davies BR. Lynch JT, et al. Among authors: davies br. Oncotarget. 2016 Apr 19;7(16):22128-39. doi: 10.18632/oncotarget.8031. Oncotarget. 2016. PMID: 26989080 Free PMC article.

6

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors.

Feng S, Shao L, Castro P, Coleman I, Nelson PS, Smith PD, Davies BR, Ittmann M. Feng S, et al. Among authors: davies br. Oncotarget. 2017 Jan 24;8(4):6179-6192. doi: 10.18632/oncotarget.14049. Oncotarget. 2017. PMID: 28008155 Free PMC article.

7

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer.

Butler DE, Marlein C, Walker HF, Frame FM, Mann VM, Simms MS, Davies BR, Collins AT, Maitland NJ. Butler DE, et al. Among authors: davies br. Oncotarget. 2017 May 23;8(34):56698-56713. doi: 10.18632/oncotarget.18082. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915623 Free PMC article.

8

Targeting castration-resistant prostate cancer with androgen receptor antisense oligonucleotide therapy.

De Velasco MA, Kura Y, Sakai K, Hatanaka Y, Davies BR, Campbell H, Klein S, Kim Y, MacLeod AR, Sugimoto K, Yoshikawa K, Nishio K, Uemura H. De Velasco MA, et al. Among authors: davies br. JCI Insight. 2019 Sep 5;4(17):e122688. doi: 10.1172/jci.insight.122688. JCI Insight. 2019. PMID: 31484823 Free PMC article.

9

Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer.

Dominguez-Escrig JL, Kelly JD, Neal DE, King SM, Davies BR. Dominguez-Escrig JL, et al. Among authors: davies br. Clin Cancer Res. 2004 Jul 15;10(14):4874-84. doi: 10.1158/1078-0432.CCR-04-0034. Clin Cancer Res. 2004. PMID: 15269164

10

Synergistic targeting of PI3K/AKT pathway and androgen receptor axis significantly delays castration-resistant prostate cancer progression in vivo.

Thomas C, Lamoureux F, Crafter C, Davies BR, Beraldi E, Fazli L, Kim S, Thaper D, Gleave ME, Zoubeidi A. Thomas C, et al. Among authors: davies br. Mol Cancer Ther. 2013 Nov;12(11):2342-55. doi: 10.1158/1535-7163.MCT-13-0032. Epub 2013 Aug 21. Mol Cancer Ther. 2013. PMID: 23966621

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