Wade M - Search Results

1

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy.

O'Neill D, Jones D, Wade M, Grey J, Nakjang S, Guo W, Cork D, Davies BR, Wedge SR, Robson CN, Gaughan L. O'Neill D, et al. Among authors: wade m. Oncotarget. 2015 Sep 22;6(28):26029-40. doi: 10.18632/oncotarget.4347. Oncotarget. 2015. PMID: 26267320 Free PMC article.

2

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer.

Jones D, Wade M, Nakjang S, Chaytor L, Grey J, Robson CN, Gaughan L. Jones D, et al. Among authors: wade m. Oncotarget. 2015 Oct 6;6(30):29782-94. doi: 10.18632/oncotarget.4927. Oncotarget. 2015. PMID: 26336819 Free PMC article.

3

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer.

Wade MA, Jones D, Wilson L, Stockley J, Coffey K, Robson CN, Gaughan L. Wade MA, et al. Nucleic Acids Res. 2015 Jan;43(1):196-207. doi: 10.1093/nar/gku1298. Epub 2014 Dec 8. Nucleic Acids Res. 2015. PMID: 25488809 Free PMC article.

4

The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer.

Jones D, Wilson L, Thomas H, Gaughan L, Wade MA. Jones D, et al. Cancers (Basel). 2019 Aug 6;11(8):1122. doi: 10.3390/cancers11081122. Cancers (Basel). 2019. PMID: 31390833 Free PMC article.

5

KDM4B is a master regulator of the estrogen receptor signalling cascade.

Gaughan L, Stockley J, Coffey K, O'Neill D, Jones DL, Wade M, Wright J, Moore M, Tse S, Rogerson L, Robson CN. Gaughan L, et al. Among authors: wade m. Nucleic Acids Res. 2013 Aug;41(14):6892-904. doi: 10.1093/nar/gkt469. Epub 2013 May 30. Nucleic Acids Res. 2013. PMID: 23723241 Free PMC article.

6

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.

Middleton FK, Patterson MJ, Elstob CJ, Fordham S, Herriott A, Wade MA, McCormick A, Edmondson R, May FE, Allan JM, Pollard JR, Curtin NJ. Middleton FK, et al. Among authors: wade ma. Oncotarget. 2015 Oct 20;6(32):32396-409. doi: 10.18632/oncotarget.6136. Oncotarget. 2015. PMID: 26486089 Free PMC article.

7

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA.

Subramanian A, Andronache A, Li YC, Wade M. Subramanian A, et al. Among authors: wade m. Oncotarget. 2016 Mar 29;7(13):15986-6002. doi: 10.18632/oncotarget.7558. Oncotarget. 2016. PMID: 26910119 Free PMC article.

8

The Epigenetic Regulatory Protein CBX2 Promotes mTORC1 Signalling and Inhibits DREAM Complex Activity to Drive Breast Cancer Cell Growth.

Bilton LJ, Warren C, Humphries RM, Kalsi S, Waters E, Francis T, Dobrowinski W, Beltran-Alvarez P, Wade MA. Bilton LJ, et al. Among authors: wade ma. Cancers (Basel). 2022 Jul 18;14(14):3491. doi: 10.3390/cancers14143491. Cancers (Basel). 2022. PMID: 35884550 Free PMC article.

9

Does radiation-induced c-MYC amplification initiate breast oncogenesis?

Wade MA, May FE, Onel K, Allan JM. Wade MA, et al. Mol Cell Oncol. 2015 Feb 3;3(1):e1010950. doi: 10.1080/23723556.2015.1010950. eCollection 2016 Jan-Feb. Mol Cell Oncol. 2015. PMID: 27308527 Free PMC article.

10

c-MYC is a radiosensitive locus in human breast cells.

Wade MA, Sunter NJ, Fordham SE, Long A, Masic D, Russell LJ, Harrison CJ, Rand V, Elstob C, Bown N, Rowe D, Lowe C, Cuthbert G, Bennett S, Crosier S, Bacon CM, Onel K, Scott K, Scott D, Travis LB, May FE, Allan JM. Wade MA, et al. Oncogene. 2015 Sep 17;34(38):4985-94. doi: 10.1038/onc.2014.427. Epub 2014 Dec 22. Oncogene. 2015. PMID: 25531321 Free PMC article.

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