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ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding.
Gong GQ, Masson GR, Lee WJ, Dickson JM, Kendall JD, Rathinaswamy MK, Buchanan CM, Middleditch M, Owen B, Spicer JA, Rewcastle GW, Denny WA, Burke JE, Shepherd PR, Williams RL, Flanagan JU. Gong GQ, et al. Among authors: lee wj. Biochem J. 2024 Nov 1:BCJ20240479. doi: 10.1042/BCJ20240479. Online ahead of print. Biochem J. 2024. PMID: 39485310
4,355 results