Liang H - Search Results

1

Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation.

Šolman M, Ligabue A, Blaževitš O, Jaiswal A, Zhou Y, Liang H, Lectez B, Kopra K, Guzmán C, Härmä H, Hancock JF, Aittokallio T, Abankwa D. Šolman M, et al. Among authors: liang h. Elife. 2015 Aug 14;4:e08905. doi: 10.7554/eLife.08905. Elife. 2015. PMID: 26274561 Free PMC article.

2

Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation.

Ariotti N, Liang H, Xu Y, Zhang Y, Yonekubo Y, Inder K, Du G, Parton RG, Hancock JF, Plowman SJ. Ariotti N, et al. Among authors: liang h. Mol Cell Biol. 2010 Aug;30(15):3795-804. doi: 10.1128/MCB.01615-09. Epub 2010 Jun 1. Mol Cell Biol. 2010. PMID: 20516214 Free PMC article.

3

H-Ras nanocluster stability regulates the magnitude of MAPK signal output.

Rotblat B, Belanis L, Liang H, Haklai R, Elad-Zefadia G, Hancock JF, Kloog Y, Plowman SJ. Rotblat B, et al. Among authors: liang h. PLoS One. 2010 Aug 5;5(8):e11991. doi: 10.1371/journal.pone.0011991. PLoS One. 2010. PMID: 20700538 Free PMC article.

4

Bile acids modulate signaling by functional perturbation of plasma membrane domains.

Zhou Y, Maxwell KN, Sezgin E, Lu M, Liang H, Hancock JF, Dial EJ, Lichtenberger LM, Levental I. Zhou Y, et al. Among authors: liang h. J Biol Chem. 2013 Dec 13;288(50):35660-70. doi: 10.1074/jbc.M113.519116. Epub 2013 Oct 28. J Biol Chem. 2013. PMID: 24165125 Free PMC article.

5

Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters.

Zhou Y, Liang H, Rodkey T, Ariotti N, Parton RG, Hancock JF. Zhou Y, et al. Among authors: liang h. Mol Cell Biol. 2014 Mar;34(5):862-76. doi: 10.1128/MCB.01227-13. Epub 2013 Dec 23. Mol Cell Biol. 2014. PMID: 24366544 Free PMC article.

6

SIGNAL TRANSDUCTION. Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling.

Zhou Y, Wong CO, Cho KJ, van der Hoeven D, Liang H, Thakur DP, Luo J, Babic M, Zinsmaier KE, Zhu MX, Hu H, Venkatachalam K, Hancock JF. Zhou Y, et al. Among authors: liang h. Science. 2015 Aug 21;349(6250):873-6. doi: 10.1126/science.aaa5619. Science. 2015. PMID: 26293964 Free PMC article.

7

Oncogenic K-Ras Binds to an Anionic Membrane in Two Distinct Orientations: A Molecular Dynamics Analysis.

Prakash P, Zhou Y, Liang H, Hancock JF, Gorfe AA. Prakash P, et al. Among authors: liang h. Biophys J. 2016 Mar 8;110(5):1125-38. doi: 10.1016/j.bpj.2016.01.019. Biophys J. 2016. PMID: 26958889 Free PMC article.

8

Lipid-Sorting Specificity Encoded in K-Ras Membrane Anchor Regulates Signal Output.

Zhou Y, Prakash P, Liang H, Cho KJ, Gorfe AA, Hancock JF. Zhou Y, et al. Among authors: liang h. Cell. 2017 Jan 12;168(1-2):239-251.e16. doi: 10.1016/j.cell.2016.11.059. Epub 2016 Dec 29. Cell. 2017. PMID: 28041850 Free PMC article.

9

Bile acids target proteolipid nano-assemblies of EGFR and phosphatidic acid in the plasma membrane for stimulation of MAPK signaling.

Liang H, Estes MK, Zhang H, Du G, Zhou Y. Liang H, et al. PLoS One. 2018 Aug 31;13(8):e0198983. doi: 10.1371/journal.pone.0198983. eCollection 2018. PLoS One. 2018. PMID: 30169511 Free PMC article.

10

Dynamics of Membrane-Bound G12V-KRAS from Simulations and Single-Molecule FRET in Native Nanodiscs.

Prakash P, Litwin D, Liang H, Sarkar-Banerjee S, Dolino D, Zhou Y, Hancock JF, Jayaraman V, Gorfe AA. Prakash P, et al. Among authors: liang h. Biophys J. 2019 Jan 22;116(2):179-183. doi: 10.1016/j.bpj.2018.12.011. Epub 2018 Dec 20. Biophys J. 2019. PMID: 30616834 Free PMC article.

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