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Page 1
The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes.
Ganapathi L, Van Haren S, Dowling DJ, Bergelson I, Shukla NM, Malladi SS, Balakrishna R, Tanji H, Ohto U, Shimizu T, David SA, Levy O. Ganapathi L, et al. Among authors: bergelson i. PLoS One. 2015 Aug 14;10(8):e0134640. doi: 10.1371/journal.pone.0134640. eCollection 2015. PLoS One. 2015. PMID: 26274907 Free PMC article.
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses.
Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O. Dowling DJ, et al. Among authors: bergelson i. J Allergy Clin Immunol. 2017 Nov;140(5):1339-1350. doi: 10.1016/j.jaci.2016.12.985. Epub 2017 Mar 23. J Allergy Clin Immunol. 2017. PMID: 28343701 Free PMC article.
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth.
Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O. Dowling DJ, et al. Among authors: bergelson i. JCI Insight. 2017 Mar 23;2(6):e91020. doi: 10.1172/jci.insight.91020. JCI Insight. 2017. PMID: 28352660 Free PMC article.
A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity.
Dowling DJ, Sanders H, Cheng WK, Joshi S, Brightman S, Bergelson I, Pietrasanta C, van Haren SD, van Amsterdam S, Fernandez J, van den Dobbelsteen GP, Levy O. Dowling DJ, et al. Among authors: bergelson i. Front Immunol. 2016 Dec 8;7:562. doi: 10.3389/fimmu.2016.00562. eCollection 2016. Front Immunol. 2016. PMID: 28008331 Free PMC article.
Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways.
Bi D, Qiao L, Bergelson I, Ek CJ, Duan L, Zhang X, Albertsson AM, Pettengill M, Kronforst K, Ninkovic J, Goldmann D, Janzon A, Hagberg H, Wang X, Mallard C, Levy O. Bi D, et al. Among authors: bergelson i. J Infect Dis. 2015 Nov 1;212(9):1480-90. doi: 10.1093/infdis/jiv231. Epub 2015 Apr 15. J Infect Dis. 2015. PMID: 25883383 Free PMC article.
Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.
Pettengill M, Robson S, Tresenriter M, Millán JL, Usheva A, Bingham T, Belderbos M, Bergelson I, Burl S, Kampmann B, Gelinas L, Kollmann T, Bont L, Levy O. Pettengill M, et al. Among authors: bergelson i. J Biol Chem. 2013 Sep 20;288(38):27315-27326. doi: 10.1074/jbc.M113.484212. Epub 2013 Jul 29. J Biol Chem. 2013. PMID: 23897810 Free PMC article. Clinical Trial.
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