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Preparation and evaluation of novel pyrazolo[1,5-a]pyrimidine acetamides, closely related to DPA-714, as potent ligands for imaging the TSPO 18kDa with PET.
Médran-Navarrete V, Damont A, Peyronneau MA, Kuhnast B, Bernards N, Pottier G, Marguet F, Puech F, Boisgard R, Dollé F. Médran-Navarrete V, et al. Among authors: damont a. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1550-6. doi: 10.1016/j.bmcl.2014.01.080. Epub 2014 Feb 7. Bioorg Med Chem Lett. 2014. PMID: 24560538
[18F]DPA-C5yne, a novel fluorine-18-labelled analogue of DPA-714: radiosynthesis and preliminary evaluation as a radiotracer for imaging neuroinflammation with PET.
Médran-Navarrete V, Bernards N, Kuhnast B, Damont A, Pottier G, Peyronneau MA, Kassiou M, Marguet F, Puech F, Boisgard R, Dollé F. Médran-Navarrete V, et al. Among authors: damont a. J Labelled Comp Radiopharm. 2014 May 30;57(6):410-8. doi: 10.1002/jlcr.3199. Epub 2014 Apr 24. J Labelled Comp Radiopharm. 2014. PMID: 24764161
Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats.
Keller T, Krzyczmonik A, Forsback S, Picón FRL, Kirjavainen AK, Takkinen J, Rajander J, Cacheux F, Damont A, Dollé F, Rinne JO, Haaparanta-Solin M, Solin O. Keller T, et al. Among authors: damont a. Mol Imaging Biol. 2017 Oct;19(5):736-745. doi: 10.1007/s11307-016-1040-z. Mol Imaging Biol. 2017. PMID: 28083825 Free PMC article.
40 results