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Anticancer flavonoids are mouse-selective STING agonists.
Kim S, Li L, Maliga Z, Yin Q, Wu H, Mitchison TJ. Kim S, et al. Among authors: li l. ACS Chem Biol. 2013 Jul 19;8(7):1396-401. doi: 10.1021/cb400264n. Epub 2013 May 23. ACS Chem Biol. 2013. PMID: 23683494 Free PMC article.
Discovery of VH domains that allosterically inhibit ENPP1.
Solomon PE, Bracken CJ, Carozza JA, Wang H, Young EP, Wellner A, Liu CC, Sweet-Cordero EA, Li L, Wells JA. Solomon PE, et al. Among authors: li l. Nat Chem Biol. 2024 Jan;20(1):30-41. doi: 10.1038/s41589-023-01368-5. Epub 2023 Jul 3. Nat Chem Biol. 2024. PMID: 37400538 Free PMC article.
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity.
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Moya-Garzon MD, Truong SD, Chou JC, Wat LW, Chidambaranathan-Reghupaty S, Coassolo L, Xu D, Shen F, Huang W, Ramirez CB, Jang C, Li L, Svensson KJ, Fischbach MA, Long JZ. Wei W, et al. Among authors: li l. Nature. 2024 Sep;633(8028):182-188. doi: 10.1038/s41586-024-07801-6. Epub 2024 Aug 7. Nature. 2024. PMID: 39112712 Free PMC article.
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