Guo J - Search Results

1

PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.

Liu P, Gan W, Chin YR, Ogura K, Guo J, Zhang J, Wang B, Blenis J, Cantley LC, Toker A, Su B, Wei W. Liu P, et al. Among authors: guo j. Cancer Discov. 2015 Nov;5(11):1194-209. doi: 10.1158/2159-8290.CD-15-0460. Epub 2015 Aug 20. Cancer Discov. 2015. PMID: 26293922 Free PMC article.

2

Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity.

Liu P, Guo J, Gan W, Wei W. Liu P, et al. Among authors: guo j. Protein Cell. 2014 Mar;5(3):171-7. doi: 10.1007/s13238-014-0021-8. Protein Cell. 2014. PMID: 24481632 Free PMC article.

3

K-ras-driven engineered mouse models for pancreatic cancer.

Yin X, Su J, Zhou X, Guo J, Wei W, Wang Z. Yin X, et al. Among authors: guo j. Discov Med. 2015 Jan;19(102):15-21. Discov Med. 2015. PMID: 25636957 Free article. Review.

4

Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.

Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W. Liu P, et al. Among authors: guo c, guo j. Mol Cell. 2015 Feb 19;57(4):648-661. doi: 10.1016/j.molcel.2015.01.005. Epub 2015 Feb 5. Mol Cell. 2015. PMID: 25661488 Free PMC article.

5

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.

Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Zhang J, et al. Among authors: guo j. Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26. Mol Cell. 2016. PMID: 27237051 Free PMC article.

6

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.

Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M, Novak J, Cheng JQ, Toker A, Signoretti S, Zhang Q, Asara JM, Kaelin WG Jr, Wei W. Guo J, et al. Science. 2016 Aug 26;353(6302):929-32. doi: 10.1126/science.aad5755. Science. 2016. PMID: 27563096 Free PMC article.

7

New Insights into Protein Hydroxylation and Its Important Role in Human Diseases.

Zurlo G, Guo J, Takada M, Wei W, Zhang Q. Zurlo G, et al. Among authors: guo j. Biochim Biophys Acta. 2016 Dec;1866(2):208-220. doi: 10.1016/j.bbcan.2016.09.004. Epub 2016 Sep 20. Biochim Biophys Acta. 2016. PMID: 27663420 Free PMC article. Review.

8

Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.

Cheng J, Zhang T, Ji H, Tao K, Guo J, Wei W. Cheng J, et al. Among authors: guo j. Biochim Biophys Acta. 2016 Dec;1866(2):232-251. doi: 10.1016/j.bbcan.2016.09.006. Epub 2016 Sep 25. Biochim Biophys Acta. 2016. PMID: 27681874 Free PMC article. Review.

9

Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells.

Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, Hu G, Guo J. Zhang L, et al. Among authors: guo j. Cancer Lett. 2017 Apr 1;390:11-20. doi: 10.1016/j.canlet.2017.01.003. Epub 2017 Jan 13. Cancer Lett. 2017. PMID: 28089830 Free PMC article.

10

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W. Wang B, et al. Among authors: guo j. Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10. Nature. 2017. PMID: 28489822 Free PMC article.

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