Zhang S - Search Results

1

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.

Zhang S, Zhou L, Hong B, van den Heuvel AP, Prabhu VV, Warfel NA, Kline CL, Dicker DT, Kopelovich L, El-Deiry WS. Zhang S, et al. Cancer Res. 2015 Sep 15;75(18):3842-52. doi: 10.1158/0008-5472.CAN-13-1079. Epub 2015 Aug 20. Cancer Res. 2015. PMID: 26294215 Free PMC article.

2

Therapeutic targeting of the p53 pathway in cancer stem cells.

Prabhu VV, Allen JE, Hong B, Zhang S, Cheng H, El-Deiry WS. Prabhu VV, et al. Among authors: zhang s. Expert Opin Ther Targets. 2012 Dec;16(12):1161-74. doi: 10.1517/14728222.2012.726985. Epub 2012 Sep 24. Expert Opin Ther Targets. 2012. PMID: 22998602 Free PMC article. Review.

3

Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.

Hong B, Prabhu VV, Zhang S, van den Heuvel AP, Dicker DT, Kopelovich L, El-Deiry WS. Hong B, et al. Among authors: zhang s. Cancer Res. 2014 Feb 15;74(4):1153-65. doi: 10.1158/0008-5472.CAN-13-0955. Epub 2013 Nov 18. Cancer Res. 2014. PMID: 24247721 Free PMC article.

4

Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities.

Hong B, van den Heuvel AP, Prabhu VV, Zhang S, El-Deiry WS. Hong B, et al. Among authors: zhang s. Curr Drug Targets. 2014 Jan;15(1):80-9. doi: 10.2174/1389450114666140106101412. Curr Drug Targets. 2014. PMID: 24387333 Review.

5

Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation.

Prabhu VV, Hong B, Allen JE, Zhang S, Lulla AR, Dicker DT, El-Deiry WS. Prabhu VV, et al. Among authors: zhang s. Cancer Res. 2016 Apr 1;76(7):1989-99. doi: 10.1158/0008-5472.CAN-14-2430. Epub 2016 Jan 12. Cancer Res. 2016. PMID: 26759239

6

CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.

Hernandez-Borrero LJ, Zhang S, Lulla A, Dicker DT, El-Deiry WS. Hernandez-Borrero LJ, et al. Among authors: zhang s. Cell Cycle. 2018;17(5):557-567. doi: 10.1080/15384101.2017.1346762. Epub 2018 Feb 19. Cell Cycle. 2018. PMID: 28749203 Free PMC article.

7

Small-molecule CB002 restores p53 pathway signaling and represses colorectal cancer cell growth.

Richardson C, Zhang S, Hernandez Borrero LJ, El-Deiry WS. Richardson C, et al. Among authors: zhang s. Cell Cycle. 2017 Sep 17;16(18):1719-1725. doi: 10.1080/15384101.2017.1356514. Epub 2017 Jul 27. Cell Cycle. 2017. PMID: 28749206 Free PMC article.

8

Bcl-2 Protein Targeting by the p53/p21 Complex-Letter.

Hernandez Borrero LJ, Sikder R, Lulla A, Gokare P, Del Valle PR, Tian X, Zhang S, Abbosh PH, El-Deiry WS. Hernandez Borrero LJ, et al. Among authors: zhang s. Cancer Res. 2018 May 15;78(10):2770-2771. doi: 10.1158/0008-5472.CAN-17-2556. Epub 2018 Apr 27. Cancer Res. 2018. PMID: 29703721 No abstract available.

9

AMG-232 sensitizes high MDM2-expressing tumor cells to T-cell-mediated killing.

Sahin I, Zhang S, Navaraj A, Zhou L, Dizon D, Safran H, El-Deiry WS. Sahin I, et al. Among authors: zhang s. Cell Death Discov. 2020 Jul 6;6:57. doi: 10.1038/s41420-020-0292-1. eCollection 2020. Cell Death Discov. 2020. PMID: 32655895 Free PMC article.

10

Correction: AMG-232 sensitizes high MDM2-expressing tumor cells to T-cell-mediated killing.

Sahin I, Zhang S, Navaraj A, Zhou L, Dizon D, Safran H, El-Deiry WS. Sahin I, et al. Among authors: zhang s. Cell Death Discov. 2020 Aug 7;6:71. doi: 10.1038/s41420-020-00310-1. eCollection 2020. Cell Death Discov. 2020. PMID: 32802408 Free PMC article.

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