Kool J - Search Results

1

At-line coupling of LC-MS to bioaffinity and selectivity assessment for metabolic profiling of ligands towards chemokine receptors CXCR1 and CXCR2.

Mladic M, Scholten DJ, Niessen WM, Somsen GW, Smit MJ, Kool J. Mladic M, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:42-53. doi: 10.1016/j.jchromb.2015.08.004. Epub 2015 Aug 10. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26301479

2

On-line formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators.

van Liempd SM, Kool J, Niessen WM, van Elswijk DE, Irth H, Vermeulen NP. van Liempd SM, et al. Among authors: kool j. Drug Metab Dispos. 2006 Sep;34(9):1640-9. doi: 10.1124/dmd.106.010355. Epub 2006 Jun 21. Drug Metab Dispos. 2006. PMID: 16790557

3

Cytochrome P450 bio-affinity detection coupled to gradient HPLC: on-line screening of affinities to cytochrome P4501A2 and 2D6.

Kool J, van Liempd SM, Harmsen S, Beckman J, van Elswijk D, Commandeur JN, Irth H, Vermeulen NP. Kool J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):49-58. doi: 10.1016/j.jchromb.2007.08.005. Epub 2007 Aug 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17826363

4

Online screening of homogeneous catalyst performance using reaction detection mass spectrometry.

Martha CT, Elders N, Krabbe JG, Kool J, Niessen WM, Orru RV, Irth H. Martha CT, et al. Among authors: kool j. Anal Chem. 2008 Sep 15;80(18):7121-7. doi: 10.1021/ac801003h. Epub 2008 Aug 13. Anal Chem. 2008. PMID: 18698801

5

Screening of protein-ligand interactions using dynamic protein-affinity chromatography solid-phase extraction-liquid chromatography-mass spectrometry.

Jonker N, Kool J, Krabbe JG, Retra K, Lingeman H, Irth H. Jonker N, et al. Among authors: kool j. J Chromatogr A. 2008 Sep 26;1205(1-2):71-7. doi: 10.1016/j.chroma.2008.07.089. Epub 2008 Aug 7. J Chromatogr A. 2008. PMID: 18715568

6

Online magnetic bead dynamic protein-affinity selection coupled to LC-MS for the screening of pharmacologically active compounds.

Jonker N, Kretschmer A, Kool J, Fernandez A, Kloos D, Krabbe JG, Lingeman H, Irth H. Jonker N, et al. Among authors: kool j. Anal Chem. 2009 Jun 1;81(11):4263-70. doi: 10.1021/ac9000755. Anal Chem. 2009. PMID: 19476387

7

Microfractionation revisited: a 1536 well high resolution screening assay.

Giera M, Heus F, Janssen L, Kool J, Lingeman H, Irth H. Giera M, et al. Among authors: kool j. Anal Chem. 2009 Jul 1;81(13):5460-6. doi: 10.1021/ac900622b. Anal Chem. 2009. PMID: 19507859

8

Development of a selective ESI-MS derivatization reagent: synthesis and optimization for the analysis of aldehydes in biological mixtures.

Eggink M, Wijtmans M, Ekkebus R, Lingeman H, de Esch IJ, Kool J, Niessen WM, Irth H. Eggink M, et al. Among authors: kool j. Anal Chem. 2008 Dec 1;80(23):9042-51. doi: 10.1021/ac801429w. Anal Chem. 2008. PMID: 19551932

9

Development of an on-line weak-cation exchange liquid chromatography-tandem mass spectrometric method for screening aldehyde products in biological matrices.

Eggink M, Charret S, Wijtmans M, Lingeman H, Kool J, Niessen WM, Irth H. Eggink M, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 1;877(31):3937-45. doi: 10.1016/j.jchromb.2009.09.043. Epub 2009 Oct 14. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19880357

10

Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR.

de Vlieger JS, Kolkman AJ, Ampt KA, Commandeur JN, Vermeulen NP, Kool J, Wijmenga SS, Niessen WM, Irth H, Honing M. de Vlieger JS, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Mar 1;878(7-8):667-74. doi: 10.1016/j.jchromb.2010.01.035. Epub 2010 Jan 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20149764

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