Valko K - Search Results

1

Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability.

Gordon LJ, Allen M, Artursson P, Hann MM, Leavens BJ, Mateus A, Readshaw S, Valko K, Wayne GJ, West A. Gordon LJ, et al. Among authors: valko k. J Biomol Screen. 2016 Feb;21(2):156-64. doi: 10.1177/1087057115604141. Epub 2015 Sep 3. J Biomol Screen. 2016. PMID: 26336900

2

In vitro measurement of drug efficiency index to aid early lead optimization.

Valko K, Chiarparin E, Nunhuck S, Montanari D. Valko K, et al. J Pharm Sci. 2012 Nov;101(11):4155-69. doi: 10.1002/jps.23305. Epub 2012 Aug 28. J Pharm Sci. 2012. PMID: 22930396

3

How to identify and eliminate compounds with a risk of high clinical dose during the early phase of lead optimisation in drug discovery.

Teague S, Valko K. Teague S, et al. Among authors: valko k. Eur J Pharm Sci. 2017 Dec 15;110:37-50. doi: 10.1016/j.ejps.2017.02.017. Epub 2017 Feb 12. Eur J Pharm Sci. 2017. PMID: 28215942

4

[Fast liquid chromatographic method to determine compounds binding to human serum albumin].

Valkó K. Valkó K. Acta Pharm Hung. 2003;73(1):13-22. Acta Pharm Hung. 2003. PMID: 12891895 Hungarian.

5

Predictive approaches to increase absorption of compounds during lead optimisation.

Valko K, Butler J, Eddershaw P. Valko K, et al. Expert Opin Drug Discov. 2013 Oct;8(10):1225-38. doi: 10.1517/17460441.2013.815613. Epub 2013 Jul 19. Expert Opin Drug Discov. 2013. PMID: 23865945 Review.

6

Estimation of volume of distribution in humans from high throughput HPLC-based measurements of human serum albumin binding and immobilized artificial membrane partitioning.

Hollósy F, Valkó K, Hersey A, Nunhuck S, Kéri G, Bevan C. Hollósy F, et al. Among authors: valko k. J Med Chem. 2006 Nov 30;49(24):6958-71. doi: 10.1021/jm050957i. J Med Chem. 2006. PMID: 17125249

7

Two-dimensional high-performance liquid chromatographic method for assaying S-adenosyl-L-methionine and its related metabolites in tissues.

Hamedani MP, Valkó K, Qi X, Welham KJ, Gibbons WA. Hamedani MP, et al. Among authors: valko k. J Chromatogr. 1993 Sep 22;619(2):191-8. doi: 10.1016/0378-4347(93)80108-g. J Chromatogr. 1993. PMID: 8263091

8

Estimating unbound volume of distribution and tissue binding by in vitro HPLC-based human serum albumin and immobilised artificial membrane-binding measurements.

Valkó KL, Nunhuck SB, Hill AP. Valkó KL, et al. J Pharm Sci. 2011 Mar;100(3):849-62. doi: 10.1002/jps.22323. Epub 2010 Oct 1. J Pharm Sci. 2011. PMID: 20891009

9

Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity.

Valko K, Nunhuck S, Bevan C, Abraham MH, Reynolds DP. Valko K, et al. J Pharm Sci. 2003 Nov;92(11):2236-48. doi: 10.1002/jps.10494. J Pharm Sci. 2003. PMID: 14603509

10

Lipophilicity and biomimetic properties measured by HPLC to support drug discovery.

Valkó KL. Valkó KL. J Pharm Biomed Anal. 2016 Oct 25;130:35-54. doi: 10.1016/j.jpba.2016.04.009. Epub 2016 Apr 8. J Pharm Biomed Anal. 2016. PMID: 27084527 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

53 results

Search Page

Filters