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Identification of Selective ERRγ Inverse Agonists.
Kim J, Im CY, Yoo EK, Ma MJ, Kim SB, Hong E, Chin J, Hwang H, Lee S, Kim ND, Jeon JH, Lee IK, Jeon YH, Choi HS, Kim SH, Cho SJ. Kim J, et al. Among authors: kim sb, kim sh, kim nd. Molecules. 2016 Jan 12;21(1):80. doi: 10.3390/molecules21010080. Molecules. 2016. PMID: 26771593 Free PMC article.
Synthesis and biological evaluation of novel 4-hydroxytamoxifen analogs as estrogen-related receptor gamma inverse agonists.
Kim J, Chin J, Im CY, Yoo EK, Woo S, Hwang HJ, Cho JH, Seo KA, Song J, Hwang H, Kim KH, Kim ND, Yoon SK, Jeon JH, Yoon SY, Jeon YH, Choi HS, Lee IK, Kim SH, Cho SJ. Kim J, et al. Among authors: kim sh, kim nd, kim kh. Eur J Med Chem. 2016 Sep 14;120:338-52. doi: 10.1016/j.ejmech.2016.04.076. Epub 2016 May 9. Eur J Med Chem. 2016. PMID: 27236015
Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Kim J, Woo SY, Im CY, Yoo EK, Lee S, Kim HJ, Hwang HJ, Cho JH, Lee WS, Yoon H, Kim S, Kwon OB, Hwang H, Kim KH, Jeon JH, Singh TD, Kim SW, Hwang SY, Choi HS, Lee IK, Kim SH, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: kim hj, kim sw, kim sh, kim s, kim kh. J Med Chem. 2016 Nov 23;59(22):10209-10227. doi: 10.1021/acs.jmedchem.6b01204. Epub 2016 Nov 9. J Med Chem. 2016. PMID: 27805390
Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression.
Zhang Y, Kim DK, Lu Y, Jung YS, Lee JM, Kim YH, Lee YS, Kim J, Dewidar B, Jeong WI, Lee IK, Cho SJ, Dooley S, Lee CH, Li X, Choi HS. Zhang Y, et al. Among authors: kim yh, kim dk, kim j. PLoS One. 2017 Jul 27;12(7):e0182141. doi: 10.1371/journal.pone.0182141. eCollection 2017. PLoS One. 2017. PMID: 28750085 Free PMC article.
Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
Kim J, Song J, Ji HD, Yoo EK, Lee JE, Lee SB, Oh JM, Lee S, Hwang JS, Yoon H, Kim DS, Lee SJ, Jeong M, Lee S, Kim KH, Choi HS, Lee SW, Park KG, Lee IK, Kim SH, Hwang H, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: kim ds, kim sh, kim kh. J Med Chem. 2019 Feb 28;62(4):1837-1858. doi: 10.1021/acs.jmedchem.8b01296. Epub 2019 Feb 4. J Med Chem. 2019. PMID: 30657313
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