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240 results

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Page 1
Cas9 gRNA engineering for genome editing, activation and repression.
Kiani S, Chavez A, Tuttle M, Hall RN, Chari R, Ter-Ovanesyan D, Qian J, Pruitt BW, Beal J, Vora S, Buchthal J, Kowal EJ, Ebrahimkhani MR, Collins JJ, Weiss R, Church G. Kiani S, et al. Among authors: tuttle m. Nat Methods. 2015 Nov;12(11):1051-4. doi: 10.1038/nmeth.3580. Epub 2015 Sep 7. Nat Methods. 2015. PMID: 26344044 Free PMC article.
Highly efficient Cas9-mediated transcriptional programming.
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM. Chavez A, et al. Among authors: tuttle m. Nat Methods. 2015 Apr;12(4):326-8. doi: 10.1038/nmeth.3312. Epub 2015 Mar 2. Nat Methods. 2015. PMID: 25730490 Free PMC article.
Comparison of Cas9 activators in multiple species.
Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJK, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G. Chavez A, et al. Among authors: tuttle m. Nat Methods. 2016 Jul;13(7):563-567. doi: 10.1038/nmeth.3871. Epub 2016 May 23. Nat Methods. 2016. PMID: 27214048 Free PMC article.
Precise Cas9 targeting enables genomic mutation prevention.
Chavez A, Pruitt BW, Tuttle M, Shapiro RS, Cecchi RJ, Winston J, Turczyk BM, Tung M, Collins JJ, Church GM. Chavez A, et al. Among authors: tuttle m. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3669-3673. doi: 10.1073/pnas.1718148115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555762 Free PMC article.
An enhanced CRISPR repressor for targeted mammalian gene regulation.
Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM. Yeo NC, et al. Among authors: tuttle m. Nat Methods. 2018 Aug;15(8):611-616. doi: 10.1038/s41592-018-0048-5. Epub 2018 Jul 16. Nat Methods. 2018. PMID: 30013045 Free PMC article.
Automated fibril structure calculations in Xplor-NIH.
Barclay AM, Milchberg MH, Warmuth OA, Tuttle MD, Dennis CJ, Schwieters CD, Rienstra CM. Barclay AM, et al. Among authors: tuttle md. Structure. 2024 Dec 9:S0969-2126(24)00501-X. doi: 10.1016/j.str.2024.11.011. Online ahead of print. Structure. 2024. PMID: 39662464
Complete genome sequence of Sporosarcina pasteurii type strain DSM33.
Tuttle MJ, Stamps BW, Chodkowski JL, Mechan-Llontop ME, Shade A, Hung C-S, Gupta MK, Carter MS. Tuttle MJ, et al. Microbiol Resour Announc. 2024 Dec 12;13(12):e0084324. doi: 10.1128/mra.00843-24. Epub 2024 Nov 20. Microbiol Resour Announc. 2024. PMID: 39565125 Free PMC article.
240 results