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Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
Zhao J, Bulek K, Gulen MF, Zepp JA, Karagkounis G, Martin BN, Zhou H, Yu M, Liu X, Huang E, Fox PL, Kalady MF, Markowitz SD, Li X. Zhao J, et al. Among authors: huang e. Gastroenterology. 2015 Dec;149(7):1860-1871.e8. doi: 10.1053/j.gastro.2015.08.051. Epub 2015 Sep 5. Gastroenterology. 2015. PMID: 26344057 Free PMC article.
Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids.
Sarvestani SK, Signs SA, Lefebvre V, Mack S, Ni Y, Morton A, Chan ER, Li X, Fox P, Ting A, Kalady MF, Cruise M, Ashburn J, Stiene J, Lai W, Liska D, Xiang S, Huang EH. Sarvestani SK, et al. Oncotarget. 2018 Jun 19;9(47):28717-28730. doi: 10.18632/oncotarget.25617. eCollection 2018 Jun 19. Oncotarget. 2018. PMID: 29983891 Free PMC article.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Rana N, Privitera G, Kondolf HC, Bulek K, Lechuga S, De Salvo C, Corridoni D, Antanaviciute A, Maywald RL, Hurtado AM, Zhao J, Huang EH, Li X, Chan ER, Simmons A, Bamias G, Abbott DW, Heaney JD, Ivanov AI, Pizarro TT. Rana N, et al. Among authors: huang eh. Cell. 2022 Jan 20;185(2):283-298.e17. doi: 10.1016/j.cell.2021.12.024. Epub 2022 Jan 11. Cell. 2022. PMID: 35021065 Free PMC article.
Colon Cancer: Inflammation-Associated Cancer.
Shawki S, Ashburn J, Signs SA, Huang E. Shawki S, et al. Among authors: huang e. Surg Oncol Clin N Am. 2018 Apr;27(2):269-287. doi: 10.1016/j.soc.2017.11.003. Epub 2017 Dec 15. Surg Oncol Clin N Am. 2018. PMID: 29496089 Free PMC article. Review.
Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells.
Fisher RC, Bellamkonda K, Alex Molina L, Xiang S, Liska D, Sarvestani SK, Chakrabarti S, Berg A, Jorgensen ML, Hatala D, Chen S, Aiello A, Appelman HD, Scott EW, Huang EH. Fisher RC, et al. Neoplasia. 2019 Mar;21(3):269-281. doi: 10.1016/j.neo.2018.12.007. Epub 2019 Feb 7. Neoplasia. 2019. PMID: 30738331 Free PMC article.
A recellularized human colon model identifies cancer driver genes.
Chen HJ, Wei Z, Sun J, Bhattacharya A, Savage DJ, Serda R, Mackeyev Y, Curley SA, Bu P, Wang L, Chen S, Cohen-Gould L, Huang E, Shen X, Lipkin SM, Copeland NG, Jenkins NA, Shuler ML. Chen HJ, et al. Among authors: huang e. Nat Biotechnol. 2016 Aug;34(8):845-51. doi: 10.1038/nbt.3586. Epub 2016 Jul 11. Nat Biotechnol. 2016. PMID: 27398792 Free PMC article.
Stromal miR-20a controls paracrine CXCL8 secretion in colitis and colon cancer.
Signs SA, Fisher RC, Tran U, Chakrabarti S, Sarvestani SK, Xiang S, Liska D, Roche V, Lai W, Gittleman HR, Wessely O, Huang EH. Signs SA, et al. Oncotarget. 2018 Feb 14;9(16):13048-13059. doi: 10.18632/oncotarget.24495. eCollection 2018 Feb 27. Oncotarget. 2018. PMID: 29560130 Free PMC article.
2,700 results