Roundhill EA - Search Results

1

Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy.

Kim B, Stephen SL, Hanby AM, Horgan K, Perry SL, Richardson J, Roundhill EA, Valleley EM, Verghese ET, Williams BJ, Thorne JL, Hughes TA. Kim B, et al. Among authors: roundhill ea. BMC Cancer. 2015 Sep 11;15:634. doi: 10.1186/s12885-015-1625-y. BMC Cancer. 2015. PMID: 26362310 Free PMC article.

2

Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria.

Roundhill EA, Burchill SA. Roundhill EA, et al. Br J Cancer. 2012 Mar 13;106(6):1224-33. doi: 10.1038/bjc.2012.40. Epub 2012 Feb 21. Br J Cancer. 2012. PMID: 22353810 Free PMC article.

3

Membrane expression of MRP-1, but not MRP-1 splicing or Pgp expression, predicts survival in patients with ESFT.

Roundhill E, Burchill S. Roundhill E, et al. Br J Cancer. 2013 Jul 9;109(1):195-206. doi: 10.1038/bjc.2013.168. Epub 2013 Jun 25. Br J Cancer. 2013. PMID: 23799853 Free PMC article.

4

Localization of MRP-1 to the outer mitochondrial membrane by the chaperone protein HSP90β.

Roundhill E, Turnbull D, Burchill S. Roundhill E, et al. FASEB J. 2016 May;30(5):1712-23. doi: 10.1096/fj.15-283408. Epub 2015 Dec 31. FASEB J. 2016. PMID: 26722004

5

ABCG1 and Pgp identify drug resistant, self-renewing osteosarcoma cells.

Roundhill EA, Jabri S, Burchill SA. Roundhill EA, et al. Cancer Lett. 2019 Jul 1;453:142-157. doi: 10.1016/j.canlet.2019.03.011. Epub 2019 Mar 22. Cancer Lett. 2019. PMID: 30910588

6

Clinical trials in cancer screening, prevention and early diagnosis (SPED): a systematic mapping review.

O'Dowd EL, Merriel SWD, Cheng VWT, Khan S, Howells LM, Gopal DP, Roundhill EA, Brennan PM, Crosbie PAJ, Neal RD, Brown K, Crosbie EJ, Baldwin DR. O'Dowd EL, et al. Among authors: roundhill ea. BMC Cancer. 2023 Sep 4;23(1):820. doi: 10.1186/s12885-023-11300-8. BMC Cancer. 2023. PMID: 37667231 Free PMC article.

7

RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma.

Roundhill EA, Chicon-Bosch M, Jeys L, Parry M, Rankin KS, Droop A, Burchill SA. Roundhill EA, et al. Cell Oncol (Dordr). 2021 Oct;44(5):1065-1085. doi: 10.1007/s13402-021-00619-8. Epub 2021 Aug 17. Cell Oncol (Dordr). 2021. PMID: 34403115 Free PMC article.

8

Membrane-type 1 matrix metalloproteinase as predictor of survival and candidate therapeutic target in Ewing sarcoma.

Brookes MJ, Roundhill EA, Jeys L, Parry M, Burchill SA, Rankin KS. Brookes MJ, et al. Among authors: roundhill ea. Pediatr Blood Cancer. 2022 Dec;69(12):e29959. doi: 10.1002/pbc.29959. Epub 2022 Sep 15. Pediatr Blood Cancer. 2022. PMID: 36106829 Free article.

9

CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.

Huynh T, Murray J, Flemming CL, Kamili A, Hofmann U, Cheung L, Roundhill EA, Yu DMT, Webber HT, Schwab M, Henderson MJ, Haber M, Norris MD, Fletcher JI. Huynh T, et al. Among authors: roundhill ea. Biochem Pharmacol. 2020 Feb;172:113770. doi: 10.1016/j.bcp.2019.113770. Epub 2019 Dec 17. Biochem Pharmacol. 2020. PMID: 31862449

10

Exploiting the Stemness and Chemoresistance Transcriptome of Ewing Sarcoma to Identify Candidate Therapeutic Targets and Drug-Repurposing Candidates.

Roundhill EA, Pantziarka P, Liddle DE, Shaw LA, Albadrani G, Burchill SA. Roundhill EA, et al. Cancers (Basel). 2023 Jan 26;15(3):769. doi: 10.3390/cancers15030769. Cancers (Basel). 2023. PMID: 36765727 Free PMC article.

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