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MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer.
Thorne JL, Battaglia S, Baxter DE, Hayes JL, Hutchinson SA, Jana S, Millican-Slater RA, Smith L, Teske MC, Wastall LM, Hughes TA. Thorne JL, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):996-1006. doi: 10.1016/j.bbagrm.2018.08.005. Epub 2018 Aug 31. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 30343695
Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer.
Hutchinson SA, Websdale A, Cioccoloni G, Røberg-Larsen H, Lianto P, Kim B, Rose A, Soteriou C, Pramanik A, Wastall LM, Williams BJ, Henn MA, Chen JJ, Ma L, Moore JB, Nelson E, Hughes TA, Thorne JL. Hutchinson SA, et al. Among authors: thorne jl. Oncogene. 2021 Apr;40(16):2872-2883. doi: 10.1038/s41388-021-01720-w. Epub 2021 Mar 19. Oncogene. 2021. PMID: 33742124 Free PMC article.
Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response.
Gwili N, Jones SJ, Amri WA, Carr IM, Harris S, Hogan BV, Hughes WE, Kim B, Langlands FE, Millican-Slater RA, Pramanik A, Thorne JL, Verghese ET, Wells G, Hamza M, Younis L, El Deeb NMF, Hughes TA. Gwili N, et al. Among authors: thorne jl. Br J Cancer. 2021 Sep;125(7):983-993. doi: 10.1038/s41416-021-01484-w. Epub 2021 Jul 12. Br J Cancer. 2021. PMID: 34253873 Free PMC article.
112 results