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IL-1 beta breaks tolerance through expansion of CD25+ effector T cells.
O'Sullivan BJ, Thomas HE, Pai S, Santamaria P, Iwakura Y, Steptoe RJ, Kay TW, Thomas R. O'Sullivan BJ, et al. Among authors: thomas he, thomas r. J Immunol. 2006 Jun 15;176(12):7278-87. doi: 10.4049/jimmunol.176.12.7278. J Immunol. 2006. PMID: 16751371
Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.
Bertin-Maghit S, Pang D, O'Sullivan B, Best S, Duggan E, Paul S, Thomas H, Kay TW, Harrison LC, Steptoe R, Thomas R. Bertin-Maghit S, et al. Diabetes. 2011 Jan;60(1):248-57. doi: 10.2337/db10-0104. Epub 2010 Oct 27. Diabetes. 2011. PMID: 20980463 Free PMC article.
253 results