Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

33 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model.
Oliveira DV, Coupland KG, Shao W, Jin S, Del Gaudio F, Wang S, Fox R, Rutten JW, Sandin J, Zetterberg H, Lundkvist J, Lesnik Oberstein SA, Lendahl U, Karlström H. Oliveira DV, et al. Among authors: rutten jw. EMBO Mol Med. 2023 Feb 8;15(2):e16556. doi: 10.15252/emmm.202216556. Epub 2022 Dec 16. EMBO Mol Med. 2023. PMID: 36524456 Free PMC article.
The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation.
Rutten JW, Klever RR, Hegeman IM, Poole DS, Dauwerse HG, Broos LA, Breukel C, Aartsma-Rus AM, Verbeek JS, van der Weerd L, van Duinen SG, van den Maagdenberg AM, Lesnik Oberstein SA. Rutten JW, et al. Acta Neuropathol Commun. 2015 Dec 29;3:89. doi: 10.1186/s40478-015-0268-1. Acta Neuropathol Commun. 2015. PMID: 26715087 Free PMC article.
Correction: The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant.
Rutten JW, Van Eijsden BJ, Duering M, Jouvent E, Opherk C, Pantoni L, Federico A, Dichgans M, Markus HS, Chabriat H, Oberstein SAJL. Rutten JW, et al. Genet Med. 2019 Aug;21(8):1895. doi: 10.1038/s41436-018-0306-z. Genet Med. 2019. PMID: 30237574 Free PMC article.
Serum Neurofilament light correlates with CADASIL disease severity and survival.
Gravesteijn G, Rutten JW, Verberk IMW, Böhringer S, Liem MK, van der Grond J, Aartsma-Rus A, Teunissen CE, Lesnik Oberstein SAJ. Gravesteijn G, et al. Among authors: rutten jw. Ann Clin Transl Neurol. 2018 Nov 20;6(1):46-56. doi: 10.1002/acn3.678. eCollection 2019 Jan. Ann Clin Transl Neurol. 2018. PMID: 30656183 Free PMC article.
Progression and Classification of Granular Osmiophilic Material (GOM) Deposits in Functionally Characterized Human NOTCH3 Transgenic Mice.
Gravesteijn G, Munting LP, Overzier M, Mulder AA, Hegeman I, Derieppe M, Koster AJ, van Duinen SG, Meijer OC, Aartsma-Rus A, van der Weerd L, Jost CR, van den Maagdenberg AMJM, Rutten JW, Lesnik Oberstein SAJ. Gravesteijn G, et al. Among authors: rutten jw. Transl Stroke Res. 2020 Jun;11(3):517-527. doi: 10.1007/s12975-019-00742-7. Epub 2019 Oct 30. Transl Stroke Res. 2020. PMID: 31667734 Free PMC article.
Naturally occurring NOTCH3 exon skipping attenuates NOTCH3 protein aggregation and disease severity in CADASIL patients.
Gravesteijn G, Dauwerse JG, Overzier M, Brouwer G, Hegeman I, Mulder AA, Baas F, Kruit MC, Terwindt GM, van Duinen SG, Jost CR, Aartsma-Rus A, Lesnik Oberstein SAJ, Rutten JW. Gravesteijn G, et al. Among authors: rutten jw. Hum Mol Genet. 2020 Jul 21;29(11):1853-1863. doi: 10.1093/hmg/ddz285. Hum Mol Genet. 2020. PMID: 31960911 Free PMC article.
Eighteen-Year Disease Progression and Survival in CADASIL.
Gravesteijn G, Hack RJ, Opstal AMV, van Eijsden BJ, Middelkoop HAM, Rodriguez Girondo MDM, Aartsma-Rus A, Grond JV, Rutten JW, Oberstein SAJL. Gravesteijn G, et al. Among authors: rutten jw. J Stroke. 2021 Jan;23(1):132-134. doi: 10.5853/jos.2020.04112. Epub 2021 Jan 31. J Stroke. 2021. PMID: 33600711 Free PMC article. No abstract available.
33 results