Zhong L - Search Results

1

Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine.

Li Y, Zhu R, Wang W, Fu D, Hou J, Ji S, Chen B, Hu Z, Shao X, Yu X, Zhao Q, Zhang B, Du C, Bu Q, Hu C, Tang Y, Zhong L, Yang S, Zhao Y, Cen X. Li Y, et al. Among authors: zhong l. J Neurosci. 2015 Sep 16;35(37):12890-902. doi: 10.1523/JNEUROSCI.0246-15.2015. J Neurosci. 2015. PMID: 26377474 Free PMC article.

2

Combined SVM-based and docking-based virtual screening for retrieving novel inhibitors of c-Met.

Xie QQ, Zhong L, Pan YL, Wang XY, Zhou JP, Di-Wu L, Huang Q, Wang YL, Yang LL, Xie HZ, Yang SY. Xie QQ, et al. Among authors: zhong l. Eur J Med Chem. 2011 Sep;46(9):3675-80. doi: 10.1016/j.ejmech.2011.05.031. Epub 2011 May 25. Eur J Med Chem. 2011. PMID: 21641696

3

A prediction model of substrates and non-substrates of breast cancer resistance protein (BCRP) developed by GA-CG-SVM method.

Zhong L, Ma CY, Zhang H, Yang LJ, Wan HL, Xie QQ, Li LL, Yang SY. Zhong L, et al. Comput Biol Med. 2011 Nov;41(11):1006-13. doi: 10.1016/j.compbiomed.2011.08.009. Epub 2011 Sep 14. Comput Biol Med. 2011. PMID: 21924412

4

Systems biology modeling reveals a possible mechanism of the tumor cell death upon oncogene inactivation in EGFR addicted cancers.

Zhou JP, Chen X, Feng S, Luo SD, Pan YL, Zhong L, Ji P, Wang ZR, Ma S, Li LL, Wei YQ, Yang SY. Zhou JP, et al. Among authors: zhong l. PLoS One. 2011;6(12):e28930. doi: 10.1371/journal.pone.0028930. Epub 2011 Dec 14. PLoS One. 2011. PMID: 22194952 Free PMC article.

5

Identification of CK2 inhibitors with new scaffolds by a hybrid virtual screening approach based on Bayesian model; pharmacophore hypothesis and molecular docking.

Di-wu L, Li LL, Wang WJ, Xie HZ, Yang J, Zhang CH, Huang Q, Zhong L, Feng S, Yang SY. Di-wu L, et al. Among authors: zhong l. J Mol Graph Model. 2012 Jun;36:42-7. doi: 10.1016/j.jmgm.2012.03.004. Epub 2012 Mar 26. J Mol Graph Model. 2012. PMID: 22516037

6

Structural optimization and structure-activity relationships of N2-(4-(4-Methylpiperazin-1-yl)phenyl)-N8-phenyl-9H-purine-2,8-diamine derivatives, a new class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations.

Yang J, Wang LJ, Liu JJ, Zhong L, Zheng RL, Xu Y, Ji P, Zhang CH, Wang WJ, Lin XD, Li LL, Wei YQ, Yang SY. Yang J, et al. Among authors: zhong l. J Med Chem. 2012 Dec 13;55(23):10685-99. doi: 10.1021/jm301365e. Epub 2012 Nov 16. J Med Chem. 2012. PMID: 23116168

7

SC-535, a novel oral multikinase inhibitor, showed potent antitumor activity in human melanoma models.

Chen X, Ji P, Yang HW, Yang LL, Zhou S, Zhong L, Ma S, Fu XY, Zhou C, Li GB, Zheng MW, Wei YQ, Yang SY. Chen X, et al. Among authors: zhong l. Cell Physiol Biochem. 2013;32(1):138-53. doi: 10.1159/000350123. Epub 2013 Jul 12. Cell Physiol Biochem. 2013. PMID: 23867251 Free article.

8

A preclinical evaluation of a novel multikinase inhibitor, SKLB-329, as a therapeutic agent against hepatocellular carcinoma.

Zhong L, Fu XY, Zou C, Yang LL, Zhou S, Yang J, Tang Y, Cheng C, Li LL, Xiang R, Chen LJ, Chen YZ, Wei YQ, Yang SY. Zhong L, et al. Int J Cancer. 2014 Dec 15;135(12):2972-83. doi: 10.1002/ijc.28944. Epub 2014 May 12. Int J Cancer. 2014. PMID: 24789676

9

A preclinical evaluation of SKLB261, a multikinase inhibitor of EGFR/Src/VEGFR2, as a therapeutic agent against pancreatic cancer.

Pan Y, Zheng M, Zhong L, Yang J, Zhou S, Qin Y, Xiang R, Chen Y, Yang SY. Pan Y, et al. Among authors: zhong l. Mol Cancer Ther. 2015 Feb;14(2):407-18. doi: 10.1158/1535-7163.MCT-14-0485. Epub 2014 Dec 17. Mol Cancer Ther. 2015. PMID: 25519702

10

LEADOPT: an automatic tool for structure-based lead optimization, and its application in structural optimizations of VEGFR2 and SYK inhibitors.

Li GB, Ji S, Yang LL, Zhang RJ, Chen K, Zhong L, Ma S, Yang SY. Li GB, et al. Among authors: zhong l. Eur J Med Chem. 2015 Mar 26;93:523-38. doi: 10.1016/j.ejmech.2015.02.019. Epub 2015 Feb 14. Eur J Med Chem. 2015. PMID: 25743214

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