Sekine M - Search Results

1

Design, Synthesis, and Properties of Phosphoramidate 2',5'-Linked Branched RNA: Toward the Rational Design of Inhibitors of the RNA Lariat Debranching Enzyme.

Tago N, Katolik A, Clark NE, Montemayor EJ, Seio K, Sekine M, Hart PJ, Damha MJ. Tago N, et al. Among authors: sekine m. J Org Chem. 2015 Oct 16;80(20):10108-18. doi: 10.1021/acs.joc.5b01719. Epub 2015 Sep 30. J Org Chem. 2015. PMID: 26378468 Free PMC article.

2

Proton-block strategy for the synthesis of oligodeoxynucleotides without base protection, capping reaction, and P-N bond cleavage reaction.

Sekine M, Ohkubo A, Seio K. Sekine M, et al. J Org Chem. 2003 Jul 11;68(14):5478-92. doi: 10.1021/jo034204k. J Org Chem. 2003. PMID: 12839438

3

A general method for the synthesis of 2'-O-cyanoethylated oligoribonucleotides having promising hybridization affinity for DNA and RNA and enhanced nuclease resistance.

Saneyoshi H, Seio K, Sekine M. Saneyoshi H, et al. Among authors: sekine m. J Org Chem. 2005 Dec 9;70(25):10453-60. doi: 10.1021/jo051741r. J Org Chem. 2005. PMID: 16323857

4

Synthesis of branched oligonucleotides with three different sequences using an oxidatively removable tritylthio group.

Utagawa E, Ohkubo A, Sekine M, Seio K. Utagawa E, et al. Among authors: sekine m. J Org Chem. 2007 Oct 26;72(22):8259-66. doi: 10.1021/jo071173a. Epub 2007 Sep 27. J Org Chem. 2007. PMID: 17900140

5

Synthesis and hybridization properties of 2'-O-methylated oligoribonucleotides incorporating 2'-O-naphthyluridines.

Sekine M, Oeda Y, Iijima Y, Taguchi H, Ohkubo A, Seio K. Sekine M, et al. Org Biomol Chem. 2011 Jan 7;9(1):210-8. doi: 10.1039/c0ob00248h. Epub 2010 Oct 29. Org Biomol Chem. 2011. PMID: 21031200

6

Synthesis of 2'-O-[2-(N-methylcarbamoyl)ethyl]ribonucleosides using oxa-Michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides.

Yamada T, Okaniwa N, Saneyoshi H, Ohkubo A, Seio K, Nagata T, Aoki Y, Takeda S, Sekine M. Yamada T, et al. Among authors: sekine m. J Org Chem. 2011 May 6;76(9):3042-53. doi: 10.1021/jo101963z. Epub 2011 Mar 23. J Org Chem. 2011. PMID: 21425877

7

Synthesis of branched DNA using oxidatively cleavable tritylsulfenyl as a hydroxy protecting group.

Seio K, Kanamori T, Sekine M. Seio K, et al. Among authors: sekine m. Curr Protoc Nucleic Acid Chem. 2014 Sep 8;58:2.18.1-19. doi: 10.1002/0471142700.nc0218s58. Curr Protoc Nucleic Acid Chem. 2014. PMID: 25199636 Review.

8

A new method for the synthesis of oligodeoxyribonucleotides containing 4-N-alkoxycarbonyldeoxycytidine derivatives and their hybridization properties.

Kobori A, Miyata K, Ushioda M, Seio K, Sekine M. Kobori A, et al. Among authors: sekine m. J Org Chem. 2002 Jan 25;67(2):476-85. doi: 10.1021/jo010813l. J Org Chem. 2002. PMID: 11798320

9

First synthesis and anticancer activity of phosmidosine and its related compounds.

Moriguchi T, Asai N, Okada K, Seio K, Sasaki T, Sekine M. Moriguchi T, et al. Among authors: sekine m. J Org Chem. 2002 May 17;67(10):3290-300. doi: 10.1021/jo016176g. J Org Chem. 2002. PMID: 12003538

10

Squaryl group as a new mimic of phosphate group in modified oligodeoxynucleotides: synthesis and properties of new oligodeoxynucleotide analogues containing an internucleotidic squaryldiamide linkage.

Sato K, Seio K, Sekine M. Sato K, et al. Among authors: sekine m. J Am Chem Soc. 2002 Oct 30;124(43):12715-24. doi: 10.1021/ja027131f. J Am Chem Soc. 2002. PMID: 12392419

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