Mattheus M - Search Results

1

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.

Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators. Zinman B, et al. Among authors: mattheus m. N Engl J Med. 2015 Nov 26;373(22):2117-28. doi: 10.1056/NEJMoa1504720. Epub 2015 Sep 17. N Engl J Med. 2015. PMID: 26378978 Free article. Clinical Trial.

2

Pharmacokinetics of empagliflozin, a sodium glucose cotransporter-2 (SGLT-2) inhibitor, coadministered with sitagliptin in healthy volunteers.

Brand T, Macha S, Mattheus M, Pinnetti S, Woerle HJ. Brand T, et al. Among authors: mattheus m. Adv Ther. 2012 Oct;29(10):889-99. doi: 10.1007/s12325-012-0055-3. Epub 2012 Oct 1. Adv Ther. 2012. PMID: 23054692 Clinical Trial.

3

Lack of drug-drug interaction between empagliflozin, a sodium glucose cotransporter 2 inhibitor, and warfarin in healthy volunteers.

Macha S, Rose P, Mattheus M, Pinnetti S, Woerle HJ. Macha S, et al. Among authors: mattheus m. Diabetes Obes Metab. 2013 Apr;15(4):316-23. doi: 10.1111/dom.12028. Epub 2012 Nov 22. Diabetes Obes Metab. 2013. PMID: 23094794

4

Pharmacokinetics of empagliflozin, a sodium glucose cotransporter-2 (SGLT2) inhibitor, and metformin following co-administration in healthy volunteers.

Macha S, Dieterich S, Mattheus M, Seman LJ, Broedl UC, Woerle HJ. Macha S, et al. Among authors: mattheus m. Int J Clin Pharmacol Ther. 2013 Feb;51(2):132-40. doi: 10.5414/CP201794. Int J Clin Pharmacol Ther. 2013. PMID: 23253948 Clinical Trial.

5

A randomized, open-label, crossover study to evaluate the pharmacokinetics of empagliflozin and linagliptin after coadministration in healthy male volunteers.

Friedrich C, Metzmann K, Rose P, Mattheus M, Pinnetti S, Woerle HJ. Friedrich C, et al. Among authors: mattheus m. Clin Ther. 2013 Jan;35(1):A33-42. doi: 10.1016/j.clinthera.2012.12.002. Clin Ther. 2013. PMID: 23328275 Clinical Trial.

6

Effect of empagliflozin on the steady-state pharmacokinetics of ethinylestradiol and levonorgestrel in healthy female volunteers.

Macha S, Mattheus M, Pinnetti S, Woerle HJ, Broedl UC. Macha S, et al. Among authors: mattheus m. Clin Drug Investig. 2013 May;33(5):351-7. doi: 10.1007/s40261-013-0068-y. Clin Drug Investig. 2013. PMID: 23512637 Clinical Trial.

7

Pharmacokinetics, pharmacodynamics and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in subjects with renal impairment.

Macha S, Mattheus M, Halabi A, Pinnetti S, Woerle HJ, Broedl UC. Macha S, et al. Among authors: mattheus m. Diabetes Obes Metab. 2014 Mar;16(3):215-22. doi: 10.1111/dom.12182. Epub 2013 Aug 19. Diabetes Obes Metab. 2014. PMID: 23859488 Clinical Trial.

8

Pharmacokinetics, safety and tolerability of empagliflozin, a sodium glucose cotransporter 2 inhibitor, in patients with hepatic impairment.

Macha S, Rose P, Mattheus M, Cinca R, Pinnetti S, Broedl UC, Woerle HJ. Macha S, et al. Among authors: mattheus m. Diabetes Obes Metab. 2014 Feb;16(2):118-23. doi: 10.1111/dom.12183. Epub 2013 Aug 19. Diabetes Obes Metab. 2014. PMID: 23859534 Clinical Trial.

9

Assessing pharmacokinetic interactions between the sodium glucose cotransporter 2 inhibitor empagliflozin and hydrochlorothiazide or torasemide in patients with type 2 diabetes mellitus: a randomized, open-label, crossover study.

Heise T, Mattheus M, Woerle HJ, Broedl UC, Macha S. Heise T, et al. Among authors: mattheus m. Clin Ther. 2015 Apr 1;37(4):793-803. doi: 10.1016/j.clinthera.2014.12.018. Epub 2015 Jan 28. Clin Ther. 2015. PMID: 25636696 Clinical Trial.

10

Design and baseline characteristics of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type 2 Diabetes (CAROLINA®).

Marx N, Rosenstock J, Kahn SE, Zinman B, Kastelein JJ, Lachin JM, Espeland MA, Bluhmki E, Mattheus M, Ryckaert B, Patel S, Johansen OE, Woerle HJ. Marx N, et al. Among authors: mattheus m. Diab Vasc Dis Res. 2015 May;12(3):164-74. doi: 10.1177/1479164115570301. Epub 2015 Mar 15. Diab Vasc Dis Res. 2015. PMID: 25780262 Free PMC article. Clinical Trial.

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