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Page 1
Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial.
Gandhi RT, Kwon DS, Macklin EA, Shopis JR, McLean AP, McBrine N, Flynn T, Peter L, Sbrolla A, Kaufmann DE, Porichis F, Walker BD, Bhardwaj N, Barouch DH, Kavanagh DG. Gandhi RT, et al. Among authors: kaufmann de. J Acquir Immune Defic Syndr. 2016 Mar 1;71(3):246-53. doi: 10.1097/QAI.0000000000000852. J Acquir Immune Defic Syndr. 2016. PMID: 26379068 Free PMC article. Clinical Trial.
Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.
Kaufmann DE, Bailey PM, Sidney J, Wagner B, Norris PJ, Johnston MN, Cosimi LA, Addo MM, Lichterfeld M, Altfeld M, Frahm N, Brander C, Sette A, Walker BD, Rosenberg ES. Kaufmann DE, et al. J Virol. 2004 May;78(9):4463-77. doi: 10.1128/jvi.78.9.4463-4477.2004. J Virol. 2004. PMID: 15078927 Free PMC article.
Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells.
Norris PJ, Moffett HF, Brander C, Allen TM, O'Sullivan KM, Cosimi LA, Kaufmann DE, Walker BD, Rosenberg ES. Norris PJ, et al. Among authors: kaufmann de. AIDS Res Hum Retroviruses. 2004 Mar;20(3):315-25. doi: 10.1089/088922204322996554. AIDS Res Hum Retroviruses. 2004. PMID: 15117455 Free PMC article.
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells.
Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, Johnston MN, Cohen D, Robbins GK, Pae E, Alter G, Wurcel A, Stone D, Rosenberg ES, Walker BD, Altfeld M. Lichterfeld M, et al. Among authors: kaufmann de. J Exp Med. 2004 Sep 20;200(6):701-12. doi: 10.1084/jem.20041270. J Exp Med. 2004. PMID: 15381726 Free PMC article.
Limited durability of viral control following treated acute HIV infection.
Kaufmann DE, Lichterfeld M, Altfeld M, Addo MM, Johnston MN, Lee PK, Wagner BS, Kalife ET, Strick D, Rosenberg ES, Walker BD. Kaufmann DE, et al. PLoS Med. 2004 Nov;1(2):e36. doi: 10.1371/journal.pmed.0010036. Epub 2004 Oct 26. PLoS Med. 2004. PMID: 15526059 Free PMC article. Clinical Trial.
Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.
Allen TM, Altfeld M, Geer SC, Kalife ET, Moore C, O'sullivan KM, Desouza I, Feeney ME, Eldridge RL, Maier EL, Kaufmann DE, Lahaie MP, Reyor L, Tanzi G, Johnston MN, Brander C, Draenert R, Rockstroh JK, Jessen H, Rosenberg ES, Mallal SA, Walker BD. Allen TM, et al. Among authors: kaufmann de. J Virol. 2005 Nov;79(21):13239-49. doi: 10.1128/JVI.79.21.13239-13249.2005. J Virol. 2005. PMID: 16227247 Free PMC article.
Expansion of HIV-specific CD4+ and CD8+ T cells by dendritic cells transfected with mRNA encoding cytoplasm- or lysosome-targeted Nef.
Kavanagh DG, Kaufmann DE, Sunderji S, Frahm N, Le Gall S, Boczkowski D, Rosenberg ES, Stone DR, Johnston MN, Wagner BS, Zaman MT, Brander C, Gilboa E, Walker BD, Bhardwaj N. Kavanagh DG, et al. Among authors: kaufmann de. Blood. 2006 Mar 1;107(5):1963-9. doi: 10.1182/blood-2005-04-1513. Epub 2005 Oct 25. Blood. 2006. PMID: 16249391 Free PMC article.
Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.
Kaufmann DE, Kavanagh DG, Pereyra F, Zaunders JJ, Mackey EW, Miura T, Palmer S, Brockman M, Rathod A, Piechocka-Trocha A, Baker B, Zhu B, Le Gall S, Waring MT, Ahern R, Moss K, Kelleher AD, Coffin JM, Freeman GJ, Rosenberg ES, Walker BD. Kaufmann DE, et al. Nat Immunol. 2007 Nov;8(11):1246-54. doi: 10.1038/ni1515. Epub 2007 Sep 30. Nat Immunol. 2007. PMID: 17906628
Increased sequence diversity coverage improves detection of HIV-specific T cell responses.
Frahm N, Kaufmann DE, Yusim K, Muldoon M, Kesmir C, Linde CH, Fischer W, Allen TM, Li B, McMahon BH, Faircloth KL, Hewitt HS, Mackey EW, Miura T, Khatri A, Wolinsky S, McMichael A, Funkhouser RK, Walker BD, Brander C, Korber BT. Frahm N, et al. Among authors: kaufmann de. J Immunol. 2007 Nov 15;179(10):6638-50. doi: 10.4049/jimmunol.179.10.6638. J Immunol. 2007. PMID: 17982054
219 results