Cummins EP - Search Results

1

Targeted delivery of the hydroxylase inhibitor DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.

Tambuwala MM, Manresa MC, Cummins EP, Aversa V, Coulter IS, Taylor CT. Tambuwala MM, et al. Among authors: cummins ep. J Control Release. 2015 Nov 10;217:221-7. doi: 10.1016/j.jconrel.2015.09.022. Epub 2015 Sep 16. J Control Release. 2015. PMID: 26385165

2

c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia.

Comerford KM, Cummins EP, Taylor CT. Comerford KM, et al. Among authors: cummins ep. Cancer Res. 2004 Dec 15;64(24):9057-61. doi: 10.1158/0008-5472.CAN-04-1919. Cancer Res. 2004. PMID: 15604272

3

Hypoxia-responsive transcription factors.

Cummins EP, Taylor CT. Cummins EP, et al. Pflugers Arch. 2005 Sep;450(6):363-71. doi: 10.1007/s00424-005-1413-7. Epub 2005 Jul 9. Pflugers Arch. 2005. PMID: 16007431 Review.

4

Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner.

O'Reilly SM, Leonard MO, Kieran N, Comerford KM, Cummins E, Pouliot M, Lee SB, Taylor CT. O'Reilly SM, et al. Am J Physiol Cell Physiol. 2006 Feb;290(2):C592-600. doi: 10.1152/ajpcell.00278.2005. Epub 2005 Oct 5. Am J Physiol Cell Physiol. 2006. PMID: 16207795 Free article.

5

Regulation of protein phosphatase 1gamma activity in hypoxia through increased interaction with NIPP1: implications for cellular metabolism.

Comerford KM, Leonard MO, Cummins EP, Fitzgerald KT, Beullens M, Bollen M, Taylor CT. Comerford KM, et al. Among authors: cummins ep. J Cell Physiol. 2006 Oct;209(1):211-8. doi: 10.1002/jcp.20726. J Cell Physiol. 2006. PMID: 16826568

6

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.

Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, Seeballuck F, Godson C, Nielsen JE, Moynagh P, Pouyssegur J, Taylor CT. Cummins EP, et al. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18154-9. doi: 10.1073/pnas.0602235103. Epub 2006 Nov 17. Proc Natl Acad Sci U S A. 2006. PMID: 17114296 Free PMC article.

7

Enhanced sensitivity of protein kinase B/Akt to insulin in hypoxia is independent of HIF1alpha and promotes cell viability.

Barry RE, Allan BB, Cummins EP, Kattla JJ, Giblin A, Scally N, Taylor CT, Brazil DP. Barry RE, et al. Among authors: cummins ep. Eur J Cell Biol. 2007 Jul;86(7):393-403. doi: 10.1016/j.ejcb.2007.04.006. Epub 2007 Jun 4. Eur J Cell Biol. 2007. PMID: 17544543

8

Hypoxic regulation of NF-kappaB signaling.

Cummins EP, Comerford KM, Scholz C, Bruning U, Taylor CT. Cummins EP, et al. Methods Enzymol. 2007;435:479-92. doi: 10.1016/S0076-6879(07)35025-8. Methods Enzymol. 2007. PMID: 17998070 Review.

9

The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.

Cummins EP, Seeballuck F, Keely SJ, Mangan NE, Callanan JJ, Fallon PG, Taylor CT. Cummins EP, et al. Gastroenterology. 2008 Jan;134(1):156-65. doi: 10.1053/j.gastro.2007.10.012. Epub 2007 Oct 10. Gastroenterology. 2008. PMID: 18166353

10

PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.

O'Hagan KA, Cocchiglia S, Zhdanov AV, Tambuwala MM, Cummins EP, Monfared M, Agbor TA, Garvey JF, Papkovsky DB, Taylor CT, Allan BB. O'Hagan KA, et al. Among authors: cummins ep. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2188-93. doi: 10.1073/pnas.0808801106. Epub 2009 Jan 28. Proc Natl Acad Sci U S A. 2009. PMID: 19179292 Free PMC article.

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