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The NADPH oxidase Nox4 has anti-atherosclerotic functions.
Schürmann C, Rezende F, Kruse C, Yasar Y, Löwe O, Fork C, van de Sluis B, Bremer R, Weissmann N, Shah AM, Jo H, Brandes RP, Schröder K. Schürmann C, et al. Among authors: weissmann n. Eur Heart J. 2015 Dec 21;36(48):3447-56. doi: 10.1093/eurheartj/ehv460. Epub 2015 Sep 17. Eur Heart J. 2015. PMID: 26385958 Free PMC article.
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.
Mittal M, Roth M, König P, Hofmann S, Dony E, Goyal P, Selbitz AC, Schermuly RT, Ghofrani HA, Kwapiszewska G, Kummer W, Klepetko W, Hoda MA, Fink L, Hänze J, Seeger W, Grimminger F, Schmidt HH, Weissmann N. Mittal M, et al. Among authors: weissmann n. Circ Res. 2007 Aug 3;101(3):258-67. doi: 10.1161/CIRCRESAHA.107.148015. Epub 2007 Jun 21. Circ Res. 2007. PMID: 17585072
NADPH oxidases in cardiovascular disease.
Brandes RP, Weissmann N, Schröder K. Brandes RP, et al. Among authors: weissmann n. Free Radic Biol Med. 2010 Sep 1;49(5):687-706. doi: 10.1016/j.freeradbiomed.2010.04.030. Epub 2010 May 2. Free Radic Biol Med. 2010. PMID: 20444433 Review.
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
Kleinschnitz C, Grund H, Wingler K, Armitage ME, Jones E, Mittal M, Barit D, Schwarz T, Geis C, Kraft P, Barthel K, Schuhmann MK, Herrmann AM, Meuth SG, Stoll G, Meurer S, Schrewe A, Becker L, Gailus-Durner V, Fuchs H, Klopstock T, de Angelis MH, Jandeleit-Dahm K, Shah AM, Weissmann N, Schmidt HH. Kleinschnitz C, et al. Among authors: weissmann n. PLoS Biol. 2010 Sep 21;8(9):e1000479. doi: 10.1371/journal.pbio.1000479. PLoS Biol. 2010. PMID: 20877715 Free PMC article.
Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension.
Kosanovic D, Kojonazarov B, Luitel H, Dahal BK, Sydykov A, Cornitescu T, Janssen W, Brandes RP, Davie N, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT. Kosanovic D, et al. Among authors: weissmann n. Respir Res. 2011 Jun 23;12(1):87. doi: 10.1186/1465-9921-12-87. Respir Res. 2011. PMID: 21699729 Free PMC article.
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.
Weissmann N, Sydykov A, Kalwa H, Storch U, Fuchs B, Mederos y Schnitzler M, Brandes RP, Grimminger F, Meissner M, Freichel M, Offermanns S, Veit F, Pak O, Krause KH, Schermuly RT, Brewer AC, Schmidt HH, Seeger W, Shah AM, Gudermann T, Ghofrani HA, Dietrich A. Weissmann N, et al. Nat Commun. 2012 Jan 31;3:649. doi: 10.1038/ncomms1660. Nat Commun. 2012. PMID: 22337127 Free PMC article.
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.
Schröder K, Zhang M, Benkhoff S, Mieth A, Pliquett R, Kosowski J, Kruse C, Luedike P, Michaelis UR, Weissmann N, Dimmeler S, Shah AM, Brandes RP. Schröder K, et al. Among authors: weissmann n. Circ Res. 2012 Apr 27;110(9):1217-25. doi: 10.1161/CIRCRESAHA.112.267054. Epub 2012 Mar 27. Circ Res. 2012. PMID: 22456182
394 results