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Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L. Min SW, et al. Among authors: shirakawa k. Nat Med. 2015 Oct;21(10):1154-62. doi: 10.1038/nm.3951. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390242 Free PMC article.
Epigenetic regulation of HIV latency.
Hakre S, Chavez L, Shirakawa K, Verdin E. Hakre S, et al. Among authors: shirakawa k. Curr Opin HIV AIDS. 2011 Jan;6(1):19-24. doi: 10.1097/COH.0b013e3283412384. Curr Opin HIV AIDS. 2011. PMID: 21242889 Review.
HIV latency: experimental systems and molecular models.
Hakre S, Chavez L, Shirakawa K, Verdin E. Hakre S, et al. Among authors: shirakawa k. FEMS Microbiol Rev. 2012 May;36(3):706-16. doi: 10.1111/j.1574-6976.2012.00335.x. FEMS Microbiol Rev. 2012. PMID: 22372374 Free PMC article. Review.
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV Jr, de Cabo R, Ulrich S, Akassoglou K, Verdin E. Shimazu T, et al. Among authors: shirakawa k. Science. 2013 Jan 11;339(6116):211-4. doi: 10.1126/science.1227166. Epub 2012 Dec 6. Science. 2013. PMID: 23223453 Free PMC article.
Reactivation of latent HIV by histone deacetylase inhibitors.
Shirakawa K, Chavez L, Hakre S, Calvanese V, Verdin E. Shirakawa K, et al. Trends Microbiol. 2013 Jun;21(6):277-85. doi: 10.1016/j.tim.2013.02.005. Epub 2013 Mar 18. Trends Microbiol. 2013. PMID: 23517573 Free PMC article. Review.
SIRT1 deacetylates RORγt and enhances Th17 cell generation.
Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E. Lim HW, et al. Among authors: shirakawa k. J Exp Med. 2015 May 4;212(5):607-17. doi: 10.1084/jem.20132378. Epub 2015 Apr 27. J Exp Med. 2015. PMID: 25918343 Free PMC article.
SIRT1 deacetylates RORγt and enhances Th17 cell generation.
Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E. Lim HW, et al. Among authors: shirakawa k. J Exp Med. 2015 Jun 1;212(6):973. doi: 10.1084/jem.2013237805062015c. Epub 2015 May 18. J Exp Med. 2015. PMID: 25987725 Free PMC article. No abstract available.
Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.
Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J. Wiley CD, et al. Among authors: shirakawa k. Cell Metab. 2016 Feb 9;23(2):303-14. doi: 10.1016/j.cmet.2015.11.011. Epub 2015 Dec 10. Cell Metab. 2016. PMID: 26686024 Free PMC article.
An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.
Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. Spina CA, et al. Among authors: shirakawa k. PLoS Pathog. 2013;9(12):e1003834. doi: 10.1371/journal.ppat.1003834. Epub 2013 Dec 26. PLoS Pathog. 2013. PMID: 24385908 Free PMC article.
414 results