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Early infancy microbial and metabolic alterations affect risk of childhood asthma.
Arrieta MC, Stiemsma LT, Dimitriu PA, Thorson L, Russell S, Yurist-Doutsch S, Kuzeljevic B, Gold MJ, Britton HM, Lefebvre DL, Subbarao P, Mandhane P, Becker A, McNagny KM, Sears MR, Kollmann T; CHILD Study Investigators; Mohn WW, Turvey SE, Finlay BB. Arrieta MC, et al. Among authors: mohn ww. Sci Transl Med. 2015 Sep 30;7(307):307ra152. doi: 10.1126/scitranslmed.aab2271. Sci Transl Med. 2015. PMID: 26424567
Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma.
Stiemsma LT, Arrieta MC, Dimitriu PA, Cheng J, Thorson L, Lefebvre DL, Azad MB, Subbarao P, Mandhane P, Becker A, Sears MR, Kollmann TR; Canadian Healthy Infant Longitudinal Development (CHILD) Study Investigators; Mohn WW, Finlay BB, Turvey SE. Stiemsma LT, et al. Among authors: mohn ww. Clin Sci (Lond). 2016 Dec 1;130(23):2199-2207. doi: 10.1042/CS20160349. Epub 2016 Sep 15. Clin Sci (Lond). 2016. PMID: 27634868
Reduced genetic potential for butyrate fermentation in the gut microbiome of infants who develop allergic sensitization.
Cait A, Cardenas E, Dimitriu PA, Amenyogbe N, Dai D, Cait J, Sbihi H, Stiemsma L, Subbarao P, Mandhane PJ, Becker AB, Moraes TJ, Sears MR, Lefebvre DL, Azad MB, Kollmann T, Turvey SE, Mohn WW. Cait A, et al. Among authors: mohn ww. J Allergy Clin Immunol. 2019 Dec;144(6):1638-1647.e3. doi: 10.1016/j.jaci.2019.06.029. Epub 2019 Jul 3. J Allergy Clin Immunol. 2019. PMID: 31279007 Clinical Trial.
Butyrate Shapes Immune Cell Fate and Function in Allergic Asthma.
Yip W, Hughes MR, Li Y, Cait A, Hirst M, Mohn WW, McNagny KM. Yip W, et al. Among authors: mohn ww. Front Immunol. 2021 Feb 15;12:628453. doi: 10.3389/fimmu.2021.628453. eCollection 2021. Front Immunol. 2021. PMID: 33659009 Free PMC article. Review.
147 results