Ohoka N - Search Results

1

Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton.

Misawa T, Yorioka M, Demizu Y, Noguchi-Yachide T, Ohoka N, Kurashima-Kinoshita M, Motoyoshi H, Nojiri H, Kittaka A, Makishima M, Naito M, Kurihara M. Misawa T, et al. Among authors: ohoka n. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5362-6. doi: 10.1016/j.bmcl.2015.09.030. Epub 2015 Sep 12. Bioorg Med Chem Lett. 2015. PMID: 26432035

2

Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.

Okuhira K, Fitzgerald ML, Tamehiro N, Ohoka N, Suzuki K, Sawada J, Naito M, Nishimaki-Mogami T. Okuhira K, et al. Among authors: ohoka n. J Biol Chem. 2010 May 21;285(21):16369-77. doi: 10.1074/jbc.M109.061424. Epub 2010 Mar 26. J Biol Chem. 2010. PMID: 20348106 Free PMC article.

3

Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α-induced apoptosis.

Kim S, Ohoka N, Okuhira K, Sai K, Nishimaki-Mogami T, Naito M. Kim S, et al. Among authors: ohoka n. Cancer Sci. 2010 Nov;101(11):2425-9. doi: 10.1111/j.1349-7006.2010.01697.x. Cancer Sci. 2010. PMID: 20825417 Free PMC article.

4

Tributyltin chloride induces ABCA1 expression and apolipoprotein A-I-mediated cellular cholesterol efflux by activating LXRα/RXR.

Cui H, Okuhira K, Ohoka N, Naito M, Kagechika H, Hirose A, Nishimaki-Mogami T. Cui H, et al. Among authors: ohoka n. Biochem Pharmacol. 2011 Mar 15;81(6):819-24. doi: 10.1016/j.bcp.2010.12.023. Epub 2011 Jan 8. Biochem Pharmacol. 2011. PMID: 21219878

5

Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein.

Okuhira K, Ohoka N, Sai K, Nishimaki-Mogami T, Itoh Y, Ishikawa M, Hashimoto Y, Naito M. Okuhira K, et al. Among authors: ohoka n. FEBS Lett. 2011 Apr 20;585(8):1147-52. doi: 10.1016/j.febslet.2011.03.019. Epub 2011 Mar 21. FEBS Lett. 2011. PMID: 21414315 Free article.

6

HNF4α increases liver-specific human ATP-binding cassette transporter A1 expression and cholesterol efflux to apolipoprotein A-I in response to cholesterol depletion.

Ohoka N, Okuhira K, Cui H, Wu W, Sato R, Naito M, Nishimaki-Mogami T. Ohoka N, et al. Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):1005-14. doi: 10.1161/ATVBAHA.111.238360. Epub 2012 Jan 26. Arterioscler Thromb Vasc Biol. 2012. PMID: 22282358

7

Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.

Okuhira K, Demizu Y, Hattori T, Ohoka N, Shibata N, Nishimaki-Mogami T, Okuda H, Kurihara M, Naito M. Okuhira K, et al. Among authors: ohoka n. Cancer Sci. 2013 Nov;104(11):1492-8. doi: 10.1111/cas.12272. Epub 2013 Oct 11. Cancer Sci. 2013. PMID: 23992566 Free PMC article.

8

APOLLON protein promotes early mitotic CYCLIN A degradation independent of the spindle assembly checkpoint.

Kikuchi R, Ohata H, Ohoka N, Kawabata A, Naito M. Kikuchi R, et al. Among authors: ohoka n. J Biol Chem. 2014 Feb 7;289(6):3457-67. doi: 10.1074/jbc.M113.514430. Epub 2013 Dec 3. J Biol Chem. 2014. PMID: 24302728 Free PMC article.

9

Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway.

Ohoka N, Nagai K, Hattori T, Okuhira K, Shibata N, Cho N, Naito M. Ohoka N, et al. Cell Death Dis. 2014 Nov 6;5(11):e1513. doi: 10.1038/cddis.2014.471. Cell Death Dis. 2014. PMID: 25375378 Free PMC article.

10

Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.

Hattori T, Watanabe-Takahashi M, Ohoka N, Hamabata T, Furukawa K, Nishikawa K, Naito M. Hattori T, et al. Among authors: ohoka n. FEBS Open Bio. 2015 Jun 12;5:605-14. doi: 10.1016/j.fob.2015.06.005. eCollection 2015. FEBS Open Bio. 2015. PMID: 26273560 Free PMC article.

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