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Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity.
Quast I, Keller CW, Maurer MA, Giddens JP, Tackenberg B, Wang LX, Münz C, Nimmerjahn F, Dalakas MC, Lünemann JD. Quast I, et al. Among authors: giddens jp. J Clin Invest. 2015 Nov 2;125(11):4160-70. doi: 10.1172/JCI82695. Epub 2015 Oct 5. J Clin Invest. 2015. PMID: 26436649 Free PMC article. Clinical Trial.
Modulating IgG effector function by Fc glycan engineering.
Li T, DiLillo DJ, Bournazos S, Giddens JP, Ravetch JV, Wang LX. Li T, et al. Among authors: giddens jp. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3485-3490. doi: 10.1073/pnas.1702173114. Epub 2017 Mar 13. Proc Natl Acad Sci U S A. 2017. PMID: 28289219 Free PMC article.
Glycoengineering of Antibodies for Modulating Functions.
Wang LX, Tong X, Li C, Giddens JP, Li T. Wang LX, et al. Among authors: giddens jp. Annu Rev Biochem. 2019 Jun 20;88:433-459. doi: 10.1146/annurev-biochem-062917-012911. Epub 2019 Mar 27. Annu Rev Biochem. 2019. PMID: 30917003 Free PMC article. Review.
Chemoenzymatic Fc glycosylation via engineered aldehyde tags.
Smith EL, Giddens JP, Iavarone AT, Godula K, Wang LX, Bertozzi CR. Smith EL, et al. Among authors: giddens jp. Bioconjug Chem. 2014 Apr 16;25(4):788-95. doi: 10.1021/bc500061s. Epub 2014 Apr 7. Bioconjug Chem. 2014. PMID: 24702330 Free PMC article.
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