Wang LX - Search Results

1

Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity.

Quast I, Keller CW, Maurer MA, Giddens JP, Tackenberg B, Wang LX, Münz C, Nimmerjahn F, Dalakas MC, Lünemann JD. Quast I, et al. Among authors: wang lx. J Clin Invest. 2015 Nov 2;125(11):4160-70. doi: 10.1172/JCI82695. Epub 2015 Oct 5. J Clin Invest. 2015. PMID: 26436649 Free PMC article. Clinical Trial.

2

Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.

Huang W, Giddens J, Fan SQ, Toonstra C, Wang LX. Huang W, et al. Among authors: wang lx. J Am Chem Soc. 2012 Jul 25;134(29):12308-18. doi: 10.1021/ja3051266. Epub 2012 Jul 16. J Am Chem Soc. 2012. PMID: 22747414 Free PMC article.

3

An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.

Chiang MJ, Holbert MA, Kalin JH, Ahn YH, Giddens J, Amin MN, Taylor MS, Collins SL, Chan-Li Y, Waickman A, Hsiao PY, Bolduc D, Leahy DJ, Horton MR, Wang LX, Powell JD, Cole PA. Chiang MJ, et al. Among authors: wang lx. J Am Chem Soc. 2014 Mar 5;136(9):3370-3. doi: 10.1021/ja5006674. Epub 2014 Feb 24. J Am Chem Soc. 2014. PMID: 24533830 Free PMC article.

4

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

Smith EL, Giddens JP, Iavarone AT, Godula K, Wang LX, Bertozzi CR. Smith EL, et al. Among authors: wang lx. Bioconjug Chem. 2014 Apr 16;25(4):788-95. doi: 10.1021/bc500061s. Epub 2014 Apr 7. Bioconjug Chem. 2014. PMID: 24702330 Free PMC article.

5

Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.

Trastoy B, Lomino JV, Pierce BG, Carter LG, Günther S, Giddens JP, Snyder GA, Weiss TM, Weng Z, Wang LX, Sundberg EJ. Trastoy B, et al. Among authors: wang lx. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6714-9. doi: 10.1073/pnas.1322908111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753590 Free PMC article.

6

Structural characterization of anti-inflammatory immunoglobulin G Fc proteins.

Ahmed AA, Giddens J, Pincetic A, Lomino JV, Ravetch JV, Wang LX, Bjorkman PJ. Ahmed AA, et al. Among authors: wang lx. J Mol Biol. 2014 Sep 9;426(18):3166-3179. doi: 10.1016/j.jmb.2014.07.006. Epub 2014 Jul 15. J Mol Biol. 2014. PMID: 25036289 Free PMC article.

7

Chemoenzymatic Glyco-engineering of Monoclonal Antibodies.

Giddens JP, Wang LX. Giddens JP, et al. Among authors: wang lx. Methods Mol Biol. 2015;1321:375-87. doi: 10.1007/978-1-4939-2760-9_25. Methods Mol Biol. 2015. PMID: 26082235 Free PMC article.

8

Evaluation of a glycoengineered monoclonal antibody via LC-MS analysis in combination with multiple enzymatic digestion.

Liu R, Giddens J, McClung CM, Magnelli PE, Wang LX, Guthrie EP. Liu R, et al. Among authors: wang lx. MAbs. 2016;8(2):340-6. doi: 10.1080/19420862.2015.1113361. Epub 2015 Oct 29. MAbs. 2016. PMID: 26514686 Free PMC article.

9

Endo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins.

Giddens JP, Lomino JV, Amin MN, Wang LX. Giddens JP, et al. Among authors: wang lx. J Biol Chem. 2016 Apr 22;291(17):9356-70. doi: 10.1074/jbc.M116.721597. Epub 2016 Mar 10. J Biol Chem. 2016. PMID: 26966183 Free PMC article.

10

Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling.

Li T, Tong X, Yang Q, Giddens JP, Wang LX. Li T, et al. Among authors: wang lx. J Biol Chem. 2016 Aug 5;291(32):16508-18. doi: 10.1074/jbc.M116.738765. Epub 2016 Jun 10. J Biol Chem. 2016. PMID: 27288408 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,559 results

Search Page

Filters