Watt A - Search Results

1

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration.

Murray SF, Jazayeri A, Matthes MT, Yasumura D, Yang H, Peralta R, Watt A, Freier S, Hung G, Adamson PS, Guo S, Monia BP, LaVail MM, McCaleb ML. Murray SF, et al. Among authors: watt a. Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6362-75. doi: 10.1167/iovs.15-16400. Invest Ophthalmol Vis Sci. 2015. PMID: 26436889 Free PMC article.

2

Antisense oligonucleotide inhibition of Bcl-xL and Bid expression in liver regulates responses in a mouse model of Fas-induced fulminant hepatitis.

Zhang H, Taylor J, Luther D, Johnston J, Murray S, Wyatt JR, Watt AT, Koo S, York-DeFalco C, Stecker K, Dean NM. Zhang H, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):24-33. doi: 10.1124/jpet.103.050435. Epub 2003 Jul 31. J Pharmacol Exp Ther. 2003. PMID: 12893848

3

Antisense oligonucleotide suppression of serum amyloid A reduces amyloid deposition in mice with AA amyloidosis.

Kluve-Beckerman B, Hardwick J, Du L, Benson MD, Monia BP, Watt A, Crooke RM, Mullick A. Kluve-Beckerman B, et al. Among authors: watt a. Amyloid. 2011 Sep;18(3):136-46. doi: 10.3109/13506129.2011.597464. Epub 2011 Aug 10. Amyloid. 2011. PMID: 21830877

4

Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.

Guo S, Casu C, Gardenghi S, Booten S, Aghajan M, Peralta R, Watt A, Freier S, Monia BP, Rivella S. Guo S, et al. Among authors: watt a. J Clin Invest. 2013 Apr;123(4):1531-41. doi: 10.1172/JCI66969. Epub 2013 Mar 25. J Clin Invest. 2013. PMID: 23524968 Free PMC article.

5

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS.

Østergaard ME, Southwell AL, Kordasiewicz H, Watt AT, Skotte NH, Doty CN, Vaid K, Villanueva EB, Swayze EE, Bennett CF, Hayden MR, Seth PP. Østergaard ME, et al. Nucleic Acids Res. 2013 Nov;41(21):9634-50. doi: 10.1093/nar/gkt725. Epub 2013 Aug 19. Nucleic Acids Res. 2013. PMID: 23963702 Free PMC article.

6

Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.

Guo S, Booten SL, Aghajan M, Hung G, Zhao C, Blomenkamp K, Gattis D, Watt A, Freier SM, Teckman JH, McCaleb ML, Monia BP. Guo S, et al. Among authors: watt a. J Clin Invest. 2014 Jan;124(1):251-61. doi: 10.1172/JCI67968. Epub 2013 Dec 20. J Clin Invest. 2014. PMID: 24355919 Free PMC article.

7

Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease.

Guo S, Booten SL, Watt A, Alvarado L, Freier SM, Teckman JH, McCaleb ML, Monia BP. Guo S, et al. Among authors: watt a. Rare Dis. 2014 Mar 12;2:e28511. doi: 10.4161/rdis.28511. eCollection 2014. Rare Dis. 2014. PMID: 25054094 Free PMC article.

8

Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients.

Skotte NH, Southwell AL, Østergaard ME, Carroll JB, Warby SC, Doty CN, Petoukhov E, Vaid K, Kordasiewicz H, Watt AT, Freier SM, Hung G, Seth PP, Bennett CF, Swayze EE, Hayden MR. Skotte NH, et al. PLoS One. 2014 Sep 10;9(9):e107434. doi: 10.1371/journal.pone.0107434. eCollection 2014. PLoS One. 2014. PMID: 25207939 Free PMC article.

9

Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.

Vickers TA, Freier SM, Bui HH, Watt A, Crooke ST. Vickers TA, et al. Among authors: watt a. PLoS One. 2014 Oct 15;9(10):e110615. doi: 10.1371/journal.pone.0110615. eCollection 2014. PLoS One. 2014. PMID: 25334092 Free PMC article.

10

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.

Huang L, Damle SS, Booten S, Singh P, Sabripour M, Hsu J, Jo M, Katz M, Watt A, Hart CE, Freier SM, Monia BP, Guo S. Huang L, et al. Among authors: watt a. PLoS One. 2015 Jul 24;10(7):e0132798. doi: 10.1371/journal.pone.0132798. eCollection 2015. PLoS One. 2015. PMID: 26207833 Free PMC article.

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