Clayton LK - Search Results

1

A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis.

Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, Clayton LK, Bronson R, Roberts TM, Gritsman K, Zhao JJ. Yuzugullu H, et al. Among authors: clayton lk. Nat Commun. 2015 Oct 7;6:8501. doi: 10.1038/ncomms9501. Nat Commun. 2015. PMID: 26442967 Free PMC article.

2

Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.

Gritsman K, Yuzugullu H, Von T, Yan H, Clayton L, Fritsch C, Maira SM, Hollingworth G, Choi C, Khandan T, Paktinat M, Okabe RO, Roberts TM, Zhao JJ. Gritsman K, et al. J Clin Invest. 2014 Apr;124(4):1794-809. doi: 10.1172/JCI69927. Epub 2014 Feb 24. J Clin Invest. 2014. PMID: 24569456 Free PMC article.

3

Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.

Clayton LK, Sieh M, Pious DA, Reinherz EL. Clayton LK, et al. Nature. 1989 Jun 15;339(6225):548-51. doi: 10.1038/339548a0. Nature. 1989. PMID: 2543930

4

Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding.

Clayton LK, Hussey RE, Steinbrich R, Ramachandran H, Husain Y, Reinherz EL. Clayton LK, et al. Nature. 1988 Sep 22;335(6188):363-6. doi: 10.1038/335363a0. Nature. 1988. PMID: 2843773

5

Impaired B cell development and function in the absence of IkappaBNS.

Touma M, Keskin DB, Shiroki F, Saito I, Koyasu S, Reinherz EL, Clayton LK. Touma M, et al. Among authors: clayton lk. J Immunol. 2011 Oct 15;187(8):3942-52. doi: 10.4049/jimmunol.1002109. Epub 2011 Sep 7. J Immunol. 2011. PMID: 21900180 Free PMC article.

6

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.

Rosenbauer F, Owens BM, Yu L, Tumang JR, Steidl U, Kutok JL, Clayton LK, Wagner K, Scheller M, Iwasaki H, Liu C, Hackanson B, Akashi K, Leutz A, Rothstein TL, Plass C, Tenen DG. Rosenbauer F, et al. Among authors: clayton lk. Nat Genet. 2006 Jan;38(1):27-37. doi: 10.1038/ng1679. Epub 2005 Nov 27. Nat Genet. 2006. PMID: 16311598

7

Involvement of the TCR Cbeta FG loop in thymic selection and T cell function.

Sasada T, Touma M, Chang HC, Clayton LK, Wang JH, Reinherz EL. Sasada T, et al. Among authors: clayton lk. J Exp Med. 2002 Jun 3;195(11):1419-31. doi: 10.1084/jem.20020119. J Exp Med. 2002. PMID: 12045240 Free PMC article.

8

Human immunodeficiency virus gp120 binding C'C" ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules.

Moebius U, Clayton LK, Abraham S, Diener A, Yunis JJ, Harrison SC, Reinherz EL. Moebius U, et al. Among authors: clayton lk. Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12008-12. doi: 10.1073/pnas.89.24.12008. Proc Natl Acad Sci U S A. 1992. PMID: 1465431 Free PMC article.

9

The human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure.

Moebius U, Clayton LK, Abraham S, Harrison SC, Reinherz EL. Moebius U, et al. Among authors: clayton lk. J Exp Med. 1992 Aug 1;176(2):507-17. doi: 10.1084/jem.176.2.507. J Exp Med. 1992. PMID: 1500858 Free PMC article.

10

Negative selection of thymocytes. A novel polymerase chain reaction-based molecular analysis detects requirements for macromolecular synthesis.

D'Adamio L, Clayton LK, Awad KM, Reinherz EL. D'Adamio L, et al. Among authors: clayton lk. J Immunol. 1992 Dec 1;149(11):3550-3. J Immunol. 1992. PMID: 1331238

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