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High-dose intravenous BCG vaccination induces enhanced immune signaling in the airways.
Peters JM, Irvine EB, Makatsa MS, Rosenberg JM, Wadsworth MH 2nd, Hughes TK, Sutton MS, Nyquist SK, Bromley JD, Mondal R, Roederer M, Seder RA, Darrah PA, Alter G, Seshadri C, Flynn JL, Shalek AK, Fortune SM, Bryson BD. Peters JM, et al. Among authors: irvine eb. Sci Adv. 2025 Jan 3;11(1):eadq8229. doi: 10.1126/sciadv.adq8229. Epub 2025 Jan 1. Sci Adv. 2025. PMID: 39742484 Free PMC article.
Mucosal Therapy of Multi-Drug Resistant Tuberculosis With IgA and Interferon-γ.
Tran AC, Diogo GR, Paul MJ, Copland A, Hart P, Mehta N, Irvine EB, Mussá T, Drake PMW, Ivanyi J, Alter G, Reljic R. Tran AC, et al. Among authors: irvine eb. Front Immunol. 2020 Oct 20;11:582833. doi: 10.3389/fimmu.2020.582833. eCollection 2020. Front Immunol. 2020. PMID: 33193394 Free PMC article.
Defining Discriminatory Antibody Fingerprints in Active and Latent Tuberculosis.
Nziza N, Cizmeci D, Davies L, Irvine EB, Jung W, Fenderson BA, de Kock M, Hanekom WA, Franken KLMC, Day CL, Ottenhoff THM, Alter G. Nziza N, et al. Among authors: irvine eb. Front Immunol. 2022 Apr 20;13:856906. doi: 10.3389/fimmu.2022.856906. eCollection 2022. Front Immunol. 2022. PMID: 35514994 Free PMC article.
Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques.
Irvine EB, O'Neil A, Darrah PA, Shin S, Choudhary A, Li W, Honnen W, Mehra S, Kaushal D, Gideon HP, Flynn JL, Roederer M, Seder RA, Pinter A, Fortune S, Alter G. Irvine EB, et al. Nat Immunol. 2021 Dec;22(12):1515-1523. doi: 10.1038/s41590-021-01066-1. Epub 2021 Nov 22. Nat Immunol. 2021. PMID: 34811542 Free PMC article.
Fc-engineered antibodies promote neutrophil-dependent control of Mycobacterium tuberculosis.
Irvine EB, Nikolov A, Khan MZ, Peters JM, Lu R, Sixsmith J, Wallace A, van Woudenbergh E, Shin S, Karpinski W, Hsiao JC, Casadevall A, Bryson BD, Cavacini L, Grace PS, Alter G, Fortune SM. Irvine EB, et al. Nat Microbiol. 2024 Sep;9(9):2369-2382. doi: 10.1038/s41564-024-01777-9. Epub 2024 Aug 22. Nat Microbiol. 2024. PMID: 39174703 Free PMC article.
20 results